The value of electroencephalography features in the prognostic evaluation of large hemispheric infarction patients at different time intervals.

Background: Large Hemispheric Infarction (LHI) is a devastating disease with high mortality. This study aimed to use electroencephalography (EEG) to evaluate the death risk of LHI patients and identify suitable evaluation time.

Methods: This study retrospectively collected clinical and EEG data from 73 LHI patients, dividing them into death and survival group at discharge.

Associations of Serum Isoleucine with Mild Cognitive Impairment and Alzheimer's Disease.

Background: Advances in blood biomarker discovery have enabled the improved diagnosis and prognosis of Alzheimer's disease (AD). Most branched-chain amino acids, except isoleucine (Ile), are correlated with both mild cognitive impairment (MCI) and AD. Therefore, this study investigated the association between serum Ile levels and MCI/AD.

The associations of serum valine with mild cognitive impairment and Alzheimer's disease.

Background: The introduction of metabolomics makes it possible to study the characteristic changes of peripheral metabolism in Alzheimer's disease (AD). Recent studies have found that the levels of valine are related to mild cognitive impairment (MCI) and AD.

Aims: This study aimed to further clarify the characteristics of valine levels in MCI and AD.