Publications by authors named "Xiao-Jie Ruan"
Cell Transplant
February 2022
Article Synopsis
- MsrB1 is an enzyme involved in converting sulfoxides back to methionine and is found to be highly expressed in colorectal cancer (CRC) tissues and cell lines.
- MsrB1 knockdown in CRC cell lines led to decreased cell proliferation, migration, and invasion, while increasing apoptosis and altering protein levels related to cell adhesion and epithelial-mesenchymal transition.
- The study suggests that MsrB1 influences CRC tumorigenesis through the GSK-3β/β-catenin signaling pathway, highlighting its potential as a biomarker and therapeutic target for CRC treatment.
