Objective: To investigate the effects of physicochemical properties of drug on its permeability through buccal mucosa.
Methods: Benzoic acid, caffeine and hydrocortisone were selected as model drugs and their permeability coefficients through isolated porcine buccal mucosa were determined.
Result: The permeability coefficients of benzoic acid, caffeine and hydrocortisone through isolated porcine buccal mucosa were (1.