Identification of differentially expressed genes induced by aberrant methylation in acute myeloid leukemia using integrated bioinformatics analyses.

Acute myeloid leukemia (AML) is a life-threatening hematological malignant disease. Methylation plays a crucial role in the etiology and pathogenesis of AML. The aim of the present study was to identify the aberrantly methylated differentially expressed genes (DEGs) in AML and determine the underlying mechanisms of tumorigenesis by conducting integrated bioinformatics analyses.

Pillared Graphene Sheets with High-Rate Performance as Anode Material for Lithium-Ion Batteries.

Pillared graphene composite (GP) is prepared by in situ polymerization and subsequent carbonization of graphene oxide (GO) and polyaniline (PANI) precursors. The interlayer spacing of GO layer can reach 1.418 nm with 200% increase compared with the original spacing of 0.

Microarray analysis of altered long non-coding RNA expression profile in liver cancer cells treated by ginsenoside Rh2.

Microarray expression profiles of lncRNAs and mRNAs were investigated in HepG2 cells treated with 20 μg/ml ginsenoside Rh2 as well as in ginsenoside Rh2-untreated cells. Microarray analysis showed 618 upregulated lncRNAs and 161 downregulated lncRNAs in HepG2 cells treated with ginsenoside Rh2 compared with the control group. Moreover, three differentially expressed lncRNAs were validated by quantitative real-time polymerase chain reaction (qRT-PCR).

Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure.

In congestive heart failure (CHF), carotid body (CB) chemoreceptor activity is enhanced and is associated with oscillatory (Cheyne-Stokes) breathing patterns, increased sympathetic nerve activity (SNA) and increased arrhythmia incidence. We hypothesized that denervation of the CB (CBD) chemoreceptors would reduce SNA, reduce apnoea and arrhythmia incidence and improve ventricular function in pacing-induced CHF rabbits. Resting breathing, renal SNA (RSNA) and arrhythmia incidence were measured in three groups of animals: (1) sham CHF/sham-CBD (sham-sham); (2) CHF/sham-CBD (CHF-sham); and (3) CHF/CBD (CHF-CBD).

[Contributions of medical practitioners of Xin'an area on acupuncture theory].

Contributions of Xin'an medical school and physicians to acupuncture theory were introduced in the article. Academic theories or characteristics of several physicians of Xin'an school such as YANG Xuan-cao, WU Kun, WANG Ji, WU Yi-ding, ZHENG Mei-jian and XU Chun-fu, et al were sorted out. Contributions of inheriting and illustrations on acupuncture theory were analyzed so as to expound its significance and value on modern acupucture clinic.

[The effect of vitamin E on renal ischemia/reperfusion injury in young and aged rats].

Objective: To investigate the effect of vitamin E on renal ischemia/reperfusion injury (RI/RI) in young and aged rats.

Methods: The model of (RI/RI) was induced by bilateral clamping the renal artery and vein for 45 min followed by reperfusion. The contents of BUN, Scr, MDA, SOD, NO and iNOS were measured.

[Talk about training of the clinical thinking from Yang Ji-zhou's medical records].

To probe into training of the clinical thinking of the students of modern acupuncture and moxibustion speciality, analyze YANG Ji-zhou's clinical thinking of acupuncture and moxibustion from YANG Ji-zhou's medical records in Zhenjiu Dacheng. Results indicate that YANG Ji-zhou's many points of view in clinical acupuncture and moxibustion still can enlighten the train of thought of later generations, suggesting that YANG Ji-zhou's clinical thinking is of an important practical significance for training of the clinical thinking of the students of the acupuncture and moxibustion speciality.

[Multicentral randomized controlled clinical trials about treatment of perimenopausal syndrome with electroacupuncture of sanyinjiao (SP 6)].

Objective: To evaluate the effect of electroacupuncture (EA) of Sanyinjiao (SP 6) on perimenopausal syndrome (PMS).

Methods: Multicentral randomized controlled trials and single blind test were adopted in the present study. A total of 157 PMS patients were randomly divided into EA group (n=81) and medication group (n=76) .

[Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial].

Objective: To our knowledge, there has been no clinical report of artesunate in the treatment of lung cancer. This study was designed to compare the efficacy and toxicity of artesunate combined with NP (a chemotherapy regimen of vinorelbine and cisplatin) and NP alone in the treatment of advanced non-small cell lung cancer (NSCLC).

Methods: One hundred and twenty cases of advanced NSCLC were randomly divided into simple chemotherapy group (control group, n=60) and combined artesunare with chemotherapy group (trial group, n=60).

[Effects of electroacupuncture of Sanyinjiao (SP 6) on genito-endocrine in patients with perimenopausal syndrome].

Objective: To observe the regulative effect of electroacupuncture (EA) of Sanyinjiao (SP 6) on genito-endocrine in patients with perimenopausal syndrome (PMS).

Methods: A total of 175 PMS patients (157 cases with complete data) were randomized into EA group (n=81) and medication group (n=76) according to multi-center (3 hospitals) and single-blind control trial method. EA (2/100 Hz, 8-10 mA) was applied to bilateral Sanyinjiao (SP 6) for 30 min, 3 times every week, with one month being a therapeutic course, 3 courses altogether.

Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbits.

Objectives: We investigated whether Angiotensin II (Ang II) modulates peripheral chemoreflex function through carotid body (CB) chemoreceptors in chronic heart failure (CHF).

Methods: We measured renal sympathetic nerve activity (RSNA) in response to graded hypoxia before and after intravenous administration of Ang II (20 ng/kg/min, i.v.

[Multicentral randomized controlled study on acupuncture at Sifeng (EX-UE 10) for treatment of infantile malnutrition].

Objective: To evaluate therapeutic effect of acupuncture at Sifeng (EX-UE 10) on infantile malnutrition.

Methods: Multicentral, randomized, controlled and single blind test was adopted. 222 infants of malnutrition were divided into an acupuncture group (n=110) and a medicine group (n=112).

[Simple analysis on collateral therapy in Huangdi's Internal Classic].

Collateral therapy includes treatment of diseases of collaterals, and treatment of human other diseases with collaterals as treating subjects. In collateral therapy of Huangdi's Internal Classic, collaterals were used as treating subjects, and the treatment was directly given at the collaterals of lesion; for treatment methods, acupuncture and moxibustion were adopted as main method, including pricking blood therapy, moxibustion of collaterals, acupuncture; the diseases and syndromes of treatment included diseases and syndromes of channels and collaterals, and human other diseases and syndromes; the principles of reinforcing and reducing, and the principles of treatment varying from time to time were stressed, and it indicated contraindications for treatment.

Efficacy of acupuncture and moxibustion in treating Bell's palsy: a multicenter randomized controlled trial in China.

Background: Bell's palsy involves acute facial paralysis due to inflammation of the facial nerve. Acupuncture and moxibustion (acu-moxi) is beneficial in treating facial palsy. In order to verify the efficacy of acu-moxi on Bell's palsy, a randomized single-blind, multicenter clinical trial was performed.