BACKGROUND Moxibustion therapy has been found to ameliorate clinical symptoms of functional dyspepsia (FD). We aimed to examine the regulatory effect of moxibustion on the gastrointestinal (GI) motility in FD and explore the underlying mechanism based on the hyperpolarization-activated cyclic nucleotide-gated cation channel 1 (HCN1). MATERIAL AND METHODS Moxibustion therapy was used in FD rats induced by using classic tail-pinch and irregular feeding.
View Article and Find Full Text PDFAims: The antihypertensive mechanism (s) of the epigallocatechin-3-gallate (EGCG), a major effective component in green tea, might associate with microRNAs (miRNAs). Here, we aimed to investigate which microRNA in aorta of spontaneously hypertensive rats (SHRs) were modulated by administration of EGCG and its mechanism.
Main Methods: The pharmacokinetic behaviors of EGCG and epigallocatechin (EGC) in Sprague-Dawley rats were analyzed by HPLC and DRUG AND STATISTICS software.
By retrieving the clinical research literature of treatment functional dyspepsia by traditional Chinese medicine (TCM) from January 2004 to December 2014 based on China National Knowledge Internet (CNKI), we would establish a TCM decoction database for treating functional dyspepsia in this study. One hundred and sixty-four literature were included, involving 159 prescriptions, 377 medicines, in a total of 1 990 herbs. These herbs can be divided into 18 categories according to the effectiveness; and qi-regulating herbs, blood circulation herbs, and antipyretic herbs ranked top three ones according to the frequency of usage of the herbs, whose medicine usage frequency accounted for 51.
View Article and Find Full Text PDFObjective: To observe the effect of electroacupuncture (EA) on superoxide (SOD), glutathione peroxidase (GSH-Px) activity, contents of glutathione (GSH) and malondiadehyde (MDA), and expression of tyrosine hydroxylase (TH) and apoptosis of Dopaminergic (DA) neurons in Substantia Nigra of rats with Parkinson's disease (PD).
Methods: Adult male Wistar rats were randomly divided into normal (10 rats), model (11 rats), EA (11 rats) and medication (11 rats) groups. The PD model was established by i.
Objective: To investigate the influence of electroacupuncture (EA) on lipid metabolism in both sexes of obesity model rats.
Methods: A total of 30 male and 30 female SD rats were randomized into normal control, model and EA groups respectively, with 10 rats in each group. EA (2 Hz, 1-2 mA) was applied to the ipsilateral "Zusanli" (ST 36)-"Sanyin-jiao"(SP 6) and bilateral "Fenglong" (ST 40) for 30 min, once daily for 28 days.
Objective: To observe the effect of encircled needling plus electroacupuncture (EA) of the second pair of nipples on hyperplastic mammary glands, serum estradiol (E2), progesterone (P), prolactin (PRL) and testosterone (T) contents, estrogen receptor (ER) expression of the mammary glands in mammary hyperplasia rats.
Methods: Forty Wistar rats were equally randomized into normal control, model, acupuncture and medication groups. Mammary gland hyperplasia model was established by intramuscular injection of diethylstilbestrol (0.
Objective: To observe the effects of electroacupuncture on hippocampal and cortical apoptosis in a mouse model of cerebral ischemia-reperfusion injury.
Methods: Mouse models established by repeated cerebral ischemia-reperfusion, followed by electroacupuncture at Shenshu, Geshu, and Baihui points. The control group mice were intragastrically administered Hydergine.
Objective: To observe the effect of acupuncture combined with dietary adjustments and aerobic exercise on the body weight, body mass index (BMI) and serum leptin content of patients with simple obesity, so as to evaluate the efficacy of the present therapy in the treatment of simple obesity.
Methods: A total of 61 cases of out-patients were randomly divided into control (n=30) and treatment (n=31) groups. Patients in the control group were treated with dietary adjustments and aerobic exercise everyday (30 min/d), continuously for 51 days, and those of the treatment group were treated with acupuncture [Zhong-wan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), etc.
Objective: To compare the therapeutic effects of acupuncture combined with diet adjustment and aerobic exercise and simple diet adjustment combined with aerobic exercise for treatment of simple obesity, in order to scientifically evaluate the therapeutic effect of acupuncture combined with diet adjustment and aerobic exercise for simple obesity.
Methods: Sixty-one cases were randomly divided into an observation group (31 cases) and a control group (30 cases). The control group was treated with diet adjustment combined with aerobic exercise, on the basis of this, the observation group was treated with acupuncture at Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), Zusanli (ST 36), Fenglong (ST 40) and Yinlingquan (SP 9) etc.
Objective: To observe the effect of high-frequency electroacupuncture (EA) on lipid metabolism in obesity rats.
Methods: Fifty-one SD rats were randomized into control group (n=13), model group (n=19) and EA group (n=19). Obesity model was duplicated by feeding the rats with high fat forage and subcutaneous injection of 15% glutamate sodium solution.
Objective: To compare the slimming effects of electroacupuncture of different frequencies.
Methods: The rats were randomly divided into a control group, a model group, an acupuncture group I (30 Hz), and an acupuncture group II (100 Hz). Acupoints selected were "Housanli" (ST 36), "Sanyinjiao" (SP 6), "Guanyuan" (CV 4), "Zhongwan" (CV 12).