A Comparative Metabolomics Analysis Reveals the Tissue-Specific Phenolic Profiling in Two Species.

(Rupr. Maxim.) Harms (ASH) and (Rupr.

Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.

Background: To investigate whether pyruvate-enriched oral rehydration solution (Pyr-ORS), compared with citrate-enriched ORS (Cit-ORS), improves hemodynamics and organ function by alleviating vasopermeability and plasma volume loss during intra-gastric fluid rehydration in dogs with severe burn.

Methods: Forty dogs subjected to severe burn were randomly divided into four groups (n=10): two oral rehydrated groups with Pyr-ORS and Cit-ORS (group PR and group CR), respectively, according to the Parkland formula during the first 24h after burns. Other two groups were the intravenous (IV) resuscitation (group VR) with lactated Ringer's solution with the same dosage and no fluid rehydration (group NR).