Publications by authors named "Xiao-Fen Gu"

Article Synopsis
  • This study focused on how patients with advanced colorectal cancer participate in treatment decisions and their perceptions of treatment effectiveness.
  • Data was collected from 4,533 patients across 19 hospitals using a questionnaire that noted demographics and treatment experiences between March 2020 and March 2021.
  • Findings showed that patients' involvement in decision-making varied widely, influenced by demographic factors, and that self-reported treatment efficacy decreased with subsequent treatments.
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  • - The study involved 1,688 Chinese patients with metastatic colorectal cancer (mCRC) across 19 hospitals to investigate the use of targeted therapies and the barriers they face in accessing these treatments.
  • - About 51.6% of patients began targeted therapy, with varying rates of first-, second-, and third-line treatments; common barriers included high costs and doubts about treatment effectiveness.
  • - Factors making patients less likely to start targeted therapy included older age, lower education and income levels, lack of medical insurance, and having more severe health issues; addressing cost and enhancing public education could improve treatment access.
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  • Vaccine uptake is essential for achieving herd immunity, and medical care workers (MCWs) can influence COVID-19 vaccine acceptance in the community.
  • A study of 2,681 MCWs across seven Chinese hospitals found that 82.5% were willing to receive the COVID-19 vaccine, with positive factors including trust in government recommendations and personal confidence about the vaccine.
  • The findings suggest that improving MCWs' confidence and awareness can boost vaccine acceptance, which could guide future vaccine promotion strategies.
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Background: Biomarkers are a key tool in early detection, prognostication, survival, and predicting treatment response of colorectal cancer (CRC). However, little is known about biomarker testing for CRC patients in real-life clinical practice in China. This study aimed to address the usage of biomarker testing and analyze factors related to its acceptance among Chinese patients with advanced CRC.

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Background: Colorectal cancer (CRC) causes a substantial disease burden in China. Information on the medical expenditure of CRC patients is critical for decision-makers to allocate medical resources reasonably, however, relevant data is limited in China, especially advanced CRC. The aim of this survey was to quantify the out-of-pocket medical expenditure of advanced CRC and explore associated factors.

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Background: Colorectal cancer (CRC) poses a significant public health burden worldwide. The investigation of the choice of medical facility among CRC patients is helpful for understanding access to health services and improving quality of oncology services to optimize health outcomes. However, there are limited studies on the topic.

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Background: Colorectal cancer (CRC) is one of the most common cancers in China, and most CRC patients have already reached an advanced stage by the time of initial diagnosis. Due to the loss of health as a result of cancer, it has consequence on the treatment which may affect the psychophysical and social impairment of CRC patients. These indicators (psychophysical, function and social impairment) affect the health-related quality of life (HRQOL).

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Background: The imbalanced allocation of medical resources leads to the occurrence of cross-regional healthcare-seeking in China. Due to the low cure rate, advanced colorectal cancer (CRC) patients may seek cross-regional healthcare for high-level medical facilities. Investigating status of cross-regional healthcare-seeking and its associated factors among advanced CRC patients is important for policymakers to understand access to health services and improve the quality of oncology services.

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Article Synopsis
  • Colorectal cancer (CRC) is a significant health issue in China, with a growing number of cases, yet little is known about patients' awareness and knowledge of the disease.
  • A nationwide survey involving 4,589 advanced CRC patients revealed that a majority lacked essential information about risk factors and screening for the disease prior to diagnosis.
  • Knowledge and awareness of CRC were found to be higher among patients with better education, higher income, and different occupational backgrounds, indicating a need for targeted public education efforts.
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Objective To measure the prevalence of mental health symptoms and identify the associated factors among college students at the beginning of coronavirus disease 2019(COVID-19)outbreak in China. Methods We carried out a multi-center cross-sectional study via snowball sampling and convenience sampling of the college students in different areas of China.The rates of self-reported depression,anxiety,and stress and post-traumatic stress disorder(PTSD)were assessed via the 21-item Depression-Anxiety-Stress Scale(DASS-21)and the 6-item Impact of Event Scale-Revised(IES-6),respectively.

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Background: College students are vulnerable and may experience high stress due to COVID-19, especially girls. This study aims to identify posttraumatic stress disorder (PTSD) and related factors among the target population during the initial phases of the COVID-19 pandemic.

Methods: In the initial phase of COVID-19 epidemic (February 23 to March 5, 2020), 2205 female college students from six provinces in mainland China were enrolled in this study and completed the online survey about the cognitive status of COVID-19, including the Impact of Event Scale-6, the Multidimensional Perceived Social Support Scale and a self-developed 10-item Perceived threat scale.

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Background: Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019 (COVID-19). Little is known about its exact impact on medical care workers and related factors in China. This study aims to identify the psychological impact of COVID-19 on medical care workers in China.

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