Publications by authors named "Xiao-Fei Shu"
Mil Med Res
December 2023
Article Synopsis
- Diabetic cardiomyopathy (DCM) leads to fatty acid accumulation in the heart, causing lipotoxicity that negatively affects heart function, while Adipsin may help mitigate these effects.
- A study was conducted on mice with a high-fat diet to explore how Adipsin influences DCM and identify its molecular interactions, using various advanced analytical methods.
- Results showed that Adipsin levels decreased in DCM, but increased Adipsin expression improved heart function and mitochondrial health by inhibiting the harmful interaction between Irak2 and key mitochondrial proteins.
