[Development and application of SSR markers of Saposhnikovia divaricata based on transcriptome].

Transcriptome sequencing was employed to mine the simple sequence repeat(SSR) locus information of Saposhnikovia divaricata and design specific primers, which aimed to provide a basis for the research on the genetic diversity of S. divaricata germplasm resources. The seed purity, 1 000-seed weight, germination rate, and seed vigor were determined.

Cardiovascular toxicities following the use of tyrosine kinase inhibitors in hepatocellular cancer patients: a retrospective, pharmacovigilance study.

Background: Cardiac adverse events (AEs) are common in tyrosine kinase inhibitors(TKIs). This study explored the cardiac AEs of TKIs through the Food and Drug Administration's Adverse Event Reporting System (FAERS).

Methods: Disproportionality analysis and Bayesian analysis were utilized for data mining of the suspected cardiac AEs of TKIs, based on FAERS data from January 2004 to December 2021.

[Molecular Genetic Characteristics of Acute Myeloid Leukemia Patients with Positive].

Objective: To explore mutational characteristics of acute myeloid leukemia (AML) patients with and analyze the correlation between the mutations and partial clinical characteristics.

Methods: A total of 62 AML patients with were included and 51 candidate genes were screened for their mutations using targeted next-generation sequencing (NGS). The exon 12 of , , and domains of were detected by genomic DNA-PCR combined with sanger sequencing.

SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.

With global warming, heat stress has become an important challenge for the global dairy industry. Sirtuin 3 (SIRT3), an important mitochondrial NAD+dependent decarboxylase and a major regulator of cellular energy metabolism and antioxidant defense, is integral to maintaining normal mitochondrial function. The aim of this study was to assess the protective effect of SIRT3 on damage to bovine mammary epithelial cells (BMECs) induced by heat stress and to explore its potential mechanism.

[Programmed cell death induced by drought stress in sprout tumble of Pinellia ternata].

To further study the mechanism of sprout tumble caused by drought,drought stress was simulating with 30% PEG 6000,physiological,and then the morphological changes of Pinellia ternata cells at different treatment time were detected. The results indicated that,along with the period of drought stress continued,the contents of chlorophyll and water potential were decreased,relative electrical conductivity,contents of soluble sugar and MDA increased. Sprout tumble of P.

[Effects of shading on key enzyme genesexpression and accumulation of saponins in Panax japonicus var. major].

To explore the effects of shading and the expression of key enzyme genes on the synthesis and accumulation of Panax japonicus var. major saponins, different shading treatments (0%, 30%,50%) of potted P. japonicus var.

[Flavor and meridian tropism classification analysis of Callianthemum taipaicum].

To explore the flavor and meridian tropism classification of Callianthemum taipaicum by principal components analysis(PCA) and partial least square analysis(PLS). Meanwhile,to establish a high performance liquid chromatography-tandem mass spectrometry(HPLC-ESI-MS) method for the simultaneous determination of 55 active components from 13 kinds of Ranunculaceae of Chinese traditional herbs. Samples were separated on HPLC system by Agilent 5 TC-C₁₈（2）（4.

[Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice].

Objective: To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and explore the possible mechanism.

Methods: Balb/c mouse models of asthma established using OVA received intraperitoneal injections of chloroquine, dexamethasone, or both prior to OVA challenge. Within 24 h after the final challenge, airway hyper- responsiveness (AHR) of the mice was assessed, and the total cell count and the counts of different cell populations in the bronchoalveolar lavage fluid (BALF) were determined under light microscopy.

Mysterious abrupt carbon-14 increase in coral contributed by a comet.

A large and sudden increase in radiocarbon ((14)C) around AD 773 are documented in coral skeletons from the South China Sea. The (14)C increased by ~ 15‰ during winter, and remain elevated for more than 4 months, then increased and dropped down within two months, forming a spike of 45‰ high in late spring, followed by two smaller spikes. The (14)C anomalies coincide with an historic comet collision with the Earth's atmosphere on 17 January AD 773.

[Effects of puerarin on proliferation and differentiation of umbilical cord mesenchymal stem cells into osteoblasts in vitro].

This study is to investigate the effects of puerarin on the proliferation and differentiation of umbilical cord mesenchymal stem cells (MSCs) into osteoblasts. Umbilical cord MSCs were cultured by tissue adherence and the third passage of cells was used in the experiment. The effect of puerarin on proliferation of umbilical cord MSCs was measured with MTT.

Quantitative trait loci for resistance to Pyrenophora tritici-repentis race 1 in a Chinese wheat.

Tan spot, caused by Pyrenophora tritici-repentis, is an economically important foliar disease of wheat worldwide. Eight races of the pathogen have been characterized on the basis of their ability to cause necrosis or chlorosis in a set of differential wheat lines. Race 1 produces two host-selective toxins, Ptr ToxA and Ptr ToxC, that induce necrosis and chlorosis, respectively, on leaves of sensitive wheat genotypes.

[Expression and clinical significance of platelet-derived growth factor A in placenta of pre-eclampsia.].

Objective: To investigate the expression and clinical significance of platelet-derived growth factor A (PDGF-A) on placenta tissue from pre-eclampsia.

Methods: The expression of PDGF-A in the placenta of 38 pre-eclampsia patients and 22 normal pregnant women at third trimester was detected by immunohistochemistry method.

Results: (1) PDGF-A was mainly expressed in the cytomembrane and cytoplasm of cytotrophoblasts and the endothelial cell of capillary in placenta.

catena-Poly[[(2,2'-bipyridine)-nickel(II)]-μ-2,4'-oxydibenzoato].

In the title compound, [Ni(C(14)H(8)O(5))(C(10)H(8)N(2))](n), the Ni(II) atom is six-coordinated in a slightly distorted octa-hedral geometry by four O atoms from two chelating carboxyl-ate groups of symmetry-related 2,4'-oxydibenzoate anions and by two N atoms from a 2,2'-bipyridine ligand. The Ni(II) atoms are bridged by the 2,4'-oxydibenzoate anions, resulting in the formation of helical chains parallel to [010] with a repeating unit of 15.039 (2) Å.