Publications by authors named "Xiao-Bing Song"

Article Synopsis
  • High-glucose concentrations in culture significantly altered DNA methylation in human oocytes, specifically increasing levels for Peg3 and decreasing for adiponectin compared to controls.
  • * Maternal diabetes negatively affects oocyte quality and its epigenetics, which has been observed in animal studies.
  • * The study utilized immature oocytes from patients undergoing ICSI, culturing them in varying glucose conditions to analyze the impact on DNA methylation after maturation.
View Article and Find Full Text PDF

Aim Of The Study: The aim of the study was to evaluate the effects of bolus infusion of hypertonic hydroxyethyl starches (HHESs) and continuous infusion of hypertonic saline (HTS) in the early resuscitation in crush syndrome.

Methods: A rat model of crush injury was established. Rats were randomly divided into five groups: (1) HHES group, (2) HTS group, (3) volume resuscitation group, (4) normal resuscitation (NR) group, and (5) sham group.

View Article and Find Full Text PDF

Objective: To compare the outcomes of intracytoplasmic sperm injection (ICSI) with retrieved epididymal and testicular sperm for obstructive azoospermia and with ejaculated sperm for severe oligozoospermia and asthenospermia.

Methods: We retrospectively analyzed 431 ICSI cycles, which were divided according to sperm sources into Groups A (n=287 in patients with severe oligozoospermia or asthenospermia using ejaculated sperm), B (n=109 in obstructive azoospermia patients with sperm retrieved by percutaneous epididymal sperm aspiration, PESA) and C (n=35 in obstructive azoospermia patients with sperm retrieved by testicular sperm extraction, TESE). Comparisons were made among the three groups in the rates of embryo implantation, fertilization, pregnancy, cleavage, and miscarriage.

View Article and Find Full Text PDF