Publications by authors named "Xiao Xie"

Cryptocaryoniasis, caused by the ciliate parasite Cryptocaryon irritans, poses a significant threat to the large yellow croaker (Larimichthys crocea) in intensive marine aquaculture. This study explores the interaction between skin and gill microbiota and C. irritans infection, focusing on the role of commensal microbes in disease resistance.

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Background: Skin aging results in skin barrier damage and skin wrinkles. Oral Colla Corii Asini (CCA) can show significant antiaging effects. However, few studies have investigated the skin's antiaging effects of topical CCA.

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Background: We previously described the enrichment of plasma exosome metabolites in CRPC, PCa, and TFC cohorts, and found significant differences in pyrimidine metabolites. The PMGs is associated with the clinical prognosis of several cancers, but its biological role in PCa is still unclear.

Methods: This study extracted 98 reliable PMGs, and analyzed their somatic mutations, expression levels, and prognostic significance.

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Objectives: Vaccine hesitancy persists as a significant global health concern, especially during public health crises. This study aimed to explore factors influencing vaccination acceptance during a major public health crisis and establish a model of influencing factors.

Design: A cross-sectional study.

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Reduced nicotinamide adenine dinucleotide phosphate [NAD(P)H] oxidases (NOX) are a major cellular source of reactive oxygen species, regulating vital physiological functions, whose dys-regulation leads to a plethora of major diseases. Much effort has been made to develop varied types of NOX inhibitors, but biotechnologies for spatially and temporally controlled NOX activation, however, are not readily available. We previously found that ultraviolet A (UVA) irradiation activates NOX2 in rodent mast cells, to elicit persistent calcium spikes.

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Objectives: Periampullary diverticulum (PAD) is usually incidentally discovered during abdominal imaging, gastrointestinal endoscopy, and endoscopic retrograde cholangiopancreatography (ERCP). The influence of PAD on ERCP outcomes is unclear. The aim of this systematic review and meta-analysis was to provide an up-to-date evaluation of the impact of PAD on cannulation and ERCP-related complications.

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Background: As traditional Chinese medicinal materials, E'jiao and cubilose are rich in various bioactive substances with good antioxidant, anti-inflammatory, and immune-regulating effects.

Aim: To obtain the optimal ratio of synergistic effect between E'jiao and cubilose.

Methods: The antioxidant capacity of E'jiao and cubilose digestive fluid was evaluated in vitro, as well as the intracellular oxidation balance between HSF cells and 3D whole-skin model induced by HO.

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Maps are fundamental medium to visualize and represent the real word in a simple and philosophical way. The emergence of the big data tide has made a proportion of maps generated from multiple sources, significantly enriching the dimensions and perspectives for understanding the characteristics of the real world. However, a majority of these map datasets remain undiscovered, unacquired and ineffectively used, which arises from the lack of numerous well-labelled benchmark datasets, which are of significance to implement the deep learning techniques into identifying complicated map content.

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Article Synopsis
  • Understanding protein-protein interactions (PPIs) in biomolecular condensates is essential to grasp their functions, but challenges arise due to their transient nature and diverse localizations.
  • The authors introduced a method called DenseMAP, which enhances the ability to study these interactions in specific compartments by using a targeted photocrosslinking approach.
  • DenseMAP successfully mapped protein interactions in stress granules and the nucleolus, revealing important roles of specific proteins and post-translational modifications in cellular processes and viral replication.
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The explosion in foundation poses a significant threat to people and buildings. Currently, a unified empirical prediction formula for crater in calcareous foundation has not been established. In this paper, analyzed the types and sizes of explosion crater with different scaled burial depths through field tests and numerical simulation.

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  • The study seeks to establish a reliable biomarker for diabetic nephropathy (DN) using AI-assisted imaging techniques in patients with type 2 diabetes mellitus (T2DM).
  • By analyzing data from 169 patients and employing statistical methods like random forest, researchers found significant correlations between perfusion density measurements and the presence of DN.
  • The results suggest that using ultra-widefield swept-source optical coherence tomography angiography could serve as a quick and effective noninvasive screening tool for DN in diabetic patients.
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Treatment of triple-negative breast cancer (TNBC) poses significant challenges due to its propensity for metastasis. A key impediment lies in the suppressive immune microenvironment, which fosters tumor progression. This study introduces an approach employing a dual immune-stimulatory CD73 antibody-polymeric cytotoxic drug complex (αCD73-PLG-MMAE).

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  • Methicillin-resistant Staphylococcus aureus (MRSA) is a dangerous pathogen analyzed through a study in Hebei, China, focusing on its clinical distribution and drug resistance patterns from 2018 to 2022.
  • Among 1,858 bacterial strains examined, 429 were identified as MRSA, with the highest detection rates found in sputum samples and critical care settings.
  • The study revealed increasing resistance to tetracycline and quinupristin/dalfopristin, while showing no resistance to vancomycin, teicoplanin, or linezolid, aiding in improved management of MRSA infections, especially in older patients.
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Tactics play an important role in team sports by guiding how players interact on the field. Both sports fans and experts have a demand for analyzing sports tactics. Existing approaches allow users to visually perceive the multivariate tactical effects.

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In soccer, player scouting aims to find players suitable for a team to increase the winning chance in future matches. To scout suitable players, coaches and analysts need to consider whether the players will perform well in a new team, which is hard to learn directly from their historical performances. Match simulation methods have been introduced to scout players by estimating their expected contributions to a new team.

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Pseudomonas plecoglossicida is one of most important pathogenic bacterial species in large yellow croaker and several other commercially valuable fish species. In our previous study, a GacS deficient mutant (ΔgacS) was constructed and its virulence showed substantially attenuated. In present study, the safety, immunogenicity and protective effect of the ΔgacS were evaluated in large yellow croaker as a live-attenuated vaccine candidate.

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Article Synopsis
  • The Aedes aegypti mosquito is a major vector for diseases like dengue, Zika, and yellow fever, and female blood-feeding is crucial for egg maturation and disease spread.
  • Research identified the sulfakinin receptor gene (SKR) in the A. aegypti genome, revealing its varied expression in the mosquito, especially in the central nervous system.
  • Manipulating the sulfakinin receptor affects blood meal intake, with inhibition from sulfakinin peptides, suggesting that targeting this receptor could help control mosquito populations and reduce disease transmission.
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Gully erosion is a serious global environmental problem associated with land degradation and ecosystem security. Examining the influencing factors of gullies and determining susceptibility hold significance in environmental sustainability. The study evaluates the spatial distribution, influencing factors, and susceptibility of gullies in the Sunshui River Basin in Sichuan Province, Southwest China.

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Tryptophan, commonly regarded as buried within the interior cores of proteins to maintain secondary structures, is now being recognized for its significant contributions to protein functionality. However, investigating functional tryptophan-involved interactions across the proteome and manipulating these interactions in live cells are considerable challenges. In this In Focus article, we summarize emerging advances in the field, describing innovative chemistries that leverage distinctive biochemical properties of the indole moiety for targeting and functionally manipulating tryptophan interactions.

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To enhance the appeal and informativeness of data news, there is an increasing reliance on data analysis techniques and visualizations, which poses a high demand for journalists' abilities. While numerous visual analytics systems have been developed for deriving insights, few tools specifically support and disseminate viewpoints for journalism. Thus, this work aims to facilitate the automatic creation of sports news from natural language insights.

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Table tennis is a sport that demands high levels of technical proficiency and body coordination from players. Biomechanical fingerprints can provide valuable insights into players' habitual movement patterns and characteristics, allowing them to identify and improve technical weaknesses. Despite the potential, few studies have developed effective methods for generating such fingerprints.

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The quantitative analysis of spatio-temporal variations of vegetation cover and its correlation with climate are of great significance for understanding of ecological environment, ecological civilization construction, and sustainable development in semi-arid areas. We investigated the spatio-temporal variations of normalized difference vegetation index (NDVI) and its response to climate change during 2000-2020 in Xilin Gol, Inner Mongolia, by using trend analysis, regression analysis and partial correlation analysis based on the data of MODIS-NDVI, tempe-rature, precipitation, digital elevation model. The results showed that vegetation cover in Xilin Gol had been increased from 2000 to 2020, which generally included three phases, , stable fluctuation, rapid growth, and steady growth.

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Formate is a major reactive carbon species in one-carbon metabolism, where it serves as an endogenous precursor for amino acid and nucleic acid biosynthesis and a cellular source of NAD(P)H. On the other hand, aberrant elevations in cellular formate are connected to progression of serious diseases, including cancer and Alzheimer's disease. Traditional methods for formate detection in biological environments often rely on sample destruction or extensive processing, resulting in a loss of spatiotemporal information.

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