Comparative Efficacy of Micro-Needle-Knife Therapy and Acupuncture in Acute Ankle Sprains: A Randomized Controlled Trial.

BACKGROUND Micro-needle knife (MNK) therapy releases the superficial fascia to alleviate pain and improve joint function in patients with acute ankle sprains (AAS). We aimed to evaluate the efficacy and safety of MNK therapy vs that of acupuncture. MATERIAL AND METHODS This blinded assessor, randomized controlled trial allocated 80 patients with AAS to 2 parallel groups in a 1: 1 ratio.

Nuclear Factor Erythroid 2-Related Factor 2 is Essential for Low-Normobaric Oxygen Treatment-Mediated Blood-Brain Barrier Protection Following Ischemic Stroke.

Cerebral ischemia/reperfusion (I/R) injury increases blood-brain barrier (BBB) permeability, leading to hemorrhagic transformation and brain edema. Normobaric oxygen (NBO) is a routine clinical treatment strategy for this condition. However, its neuroprotective effects remain controversial.

Complete mitochondrial genome of (Arthropoda: Dermanyssidae) isolate from China.

The complete mitochondrial genome of isolated from China is reported for the first time in this study. Its entire mitogenome is 16, 184 bp in length, contained 13 protein-coding genes, 2 ribosomal RNA genes, 21 transfer RNA genes, and 1 non-coding region. The phylogenetic analysis by maximum likelihood method show that isolated from China is in the same clade with the genus of .

The Role of Ranged Horses in Eco-Epidemiology of Infection in China.

is a tick-borne pathogen that infects humans; however, the vertebrate hosts of this pathogen have not been clearly defined. Our molecular examination of spp. infecting mammals and ticks in China, identified the A, A, and 17KD gene sequences of in horses and their ticks.

Severity of Intracranial Large Artery Disease Correlates With Cerebral Small Vessel Disease.

Background: Small vessel disease (SVD) shares common vascular risk factors with large artery disease (LAD). However, little is known about the relationship between intracranial artery stenosis and SVD burden.

Purpose: To investigate whether SVD burden correlates with severity of intracranial LAD.

Identification of Myoferlin, a Potential Serodiagnostic Antigen of Clonorchiasis, Immunoproteomic Analysis of Sera From Different Infection Periods and Excretory-Secretory Products of .

Clonorchiasis, which is caused by , is an important foodborne disease worldwide. The excretory-secretory products (ESPs) of play important roles in host-parasite interactions by acting as causative agents. In the present study, the ESPs and sera positive for were collected to identify proteins specific to the sera of (i.

Characterization of the complete mitochondrial genomes of Coronocyclus labiatus and Cylicodontophorus bicoronatus: Comparison with Strongylidae species and phylogenetic implication.

Coronocyclus labiatus and Cylicodontophorus bicoronatus are two significant horse parasitic nematodes which are classified into subfamily Cyathostominae, family Strongylidae, however, the classification of these nematodes has been controversial for more than a century. Mitochondrial (mt) genomes are considered valuable sources for parasite taxonomy, population genetics, and systematics studies. In the present study, the mt genomes of Co.

Comparative analyses of complete ribosomal DNA sequences of Clonorchis sinensis and Metorchis orientalis: IGS sequences may provide a novel genetic marker for intraspecific variation.

Both Clonorchis sinensis and Metorchis orientalis are the fish-borne zoonotic trematodes, and have a wide distribution of southeastern Asia, especially in China. Due to the similar morphology, life cycle, and parasitic positions are difficult to differentiate between both metacercariae. In the present study, the complete rDNA sequences of five C.

[The inversion of nitrogen balance index in typical growth period of soybean based on high definition digital image and hyperspectral data on unmanned aerial vehicles].

Nitrogen balance index (NBI) is one of the important indicators for crop growth. The high and low status of nitrogen can be quickly monitored by measuring NBI, which can provide accurate information of agricultural production and management. The relationship between NBI and original spectrum and derivative spectrum of infrared and near infrared wavelength from flowering to maturity stage was analyzed based on high definition digital image and hyperspectral data on unmanned aerial vehicles.

Low-dose curcumin stimulates proliferation of rat embryonic neural stem cells through glucocorticoid receptor and STAT3.

Aims: This study was to determine whether curcumin had any effect on the proliferation of neural stem cell (NSC), analyze the expression of glucocorticoid receptor (GR), signal transducer and activator of transcription 3 (STAT3), and Notch1 at transcription and protein level, and discuss the related mechanisms.

Methods And Results: NSCs were harvested from E15 SD rat brain and cultured. All experiments were performed at the second passage.

Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2.

Saccharomyces cerevisiae Gre2 (EC1.1.1.

[Trend in acid deposition at Tieshanping, Chonging during 2001-2010].

Although the total emission of sulphure dioxide (SO2) was reduced by more than 10% in the Eleventh Five-Year-Plan (2006-2010) in China, the total emission of nitrogen oxides (NOx) in the same period kept increasing. In order to evaluate the effects of the emission changes on acid depostion, a ten-year monitoring on forest throughfall was carried out from 2001 to 2010 at Tieshanping, Chongqing in Southwestern China. The results indicated there was a significantly decreasing trend of sulphur deposition and an increasing trend of nitrogen deposition, which coincided well with the dicreasing trend of SO2 emission and increasing tread of NOx emission in Chongqing, respectively.

Intracoronary fixed dose of nitroprusside via thrombus aspiration catheter for the prevention of the no-reflow phenomenon following primary percutaneous coronary intervention in acute myocardial infarction.

Previous studies have shown that intracoronary (IC) nitroprusside (NTP) injection is a safe and effective strategy for the treatment of no-reflow (NR) during percutaneous coronary intervention (PCI). The present study tested the hypothesis that, on the basis of thrombus aspiration for the treatment of ST-segment elevation myocardial infarction (STEMI), the selective IC administration of a fixed dose of NTP (100 g) plus tirofiban is a safe and superior treatment method compared with the IC administration of tirofiban alone for the prevention of NR during primary PCI. A total of 162 consecutive patients with STEMI, who underwent primary PCI within 12 h of onset, were randomly assigned to two groups: Group A, IC administration of a fixed dose of NTP (100 g) plus tirofiban (10 g/kg) and group B, IC administration of tirofiban (10 g/kg) alone (n=80 and n=82, respectively).

[Effects of simulated nitrogen deposition on organic matter leaching in forest soil].

The impact of nitrogen deposition on the dynamics of carbon pool in forest soil was studied through a field experiment at Tieshanping, Chongqing in Southwest China. The changes of dissolved organic matter (DOM) concentration in soil water in different soil layers were monitored for five years after addition of ammonium nitrate (NH4NO3) or sodium nitrate (NaNO3) at the same dose as the current nitrogen deposition to the forest floor. The results indicated that the concentration and flux of dissolved organic carbon (DOC) were increased in the first two years and then decreased by fertilizing.

A friend to the airways: a review of the emerging clinical importance of the bronchial arterial circulation.

Lungs receive the bulk of their blood supply through the pulmonary arteries. The bronchial arteries, on the other hand, vascularize the bronchi and their surroundings. These two arteries anastomose near the alveolar ducts.

Structural snapshots of yeast alkyl hydroperoxide reductase Ahp1 peroxiredoxin reveal a novel two-cysteine mechanism of electron transfer to eliminate reactive oxygen species.

Peroxiredoxins (Prxs) are thiol-specific antioxidant proteins that protect cells against reactive oxygen species and are involved in cellular signaling pathways. Alkyl hydroperoxide reductase Ahp1 belongs to the Prx5 subfamily and is a two-cysteine (2-Cys) Prx that forms an intermolecular disulfide bond. Enzymatic assays and bioinformatics enabled us to re-assign the peroxidatic cysteine (C(P)) to Cys-62 and the resolving cysteine (C(R)) to Cys-31 but not the previously reported Cys-120.

[Recent advances of studies on interaction of natural killer cells and fungi].

Natural killer (NK) cells are important innate immune effector cells with broad applications in killing the tumor cells and pathogens due to its cytotoxicity without prior immune sensitization. Unfortunately, in humans, the activity of NK cells against fungi is poorly characterized. Insight progress in the fields of NK cells activating, pattern recognition receptors, signal modulating and correlated cell factors (IFN-γ, GM-CSF, IL-10 and so on) has revolutionized understanding of the selective killing fungi by NK cells.

Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1.

Quinone oxidoreductase (QOR EC1.6.5.

Structure-guided activity restoration of the silkworm glutathione transferase Omega GSTO3-3.

Glutathione transferases (GSTs) are ubiquitous detoxification enzymes that conjugate hydrophobic xenobiotics with reduced glutathione. The silkworm Bombyx mori encodes four isoforms of GST Omega (GSTO), featured with a catalytic cysteine, except that bmGSTO3-3 has an asparagine substitution of this catalytic residue. Here, we determined the 2.

Crystal structures and putative interface of Saccharomyces cerevisiae mitochondrial matrix proteins Mmf1 and Mam33.

The yeast Saccharomyces cerevisiae mitochondrial matrix factor Mmf1, a member in the YER057c/Yigf/Uk114 family, participates in isoleucine biosynthesis and mitochondria maintenance. Mmf1 physically interacts with another mitochondrial matrix protein Mam33, which is involved in the sorting of cytochrome b₂ to the intermembrane space as well as mitochondrial ribosomal protein synthesis. To elucidate the structural basis for their interaction, we determined the crystal structures of Mmf1 and Mam33 at 1.

Crystal structure of the 30 K protein from the silkworm Bombyx mori reveals a new member of the β-trefoil superfamily.

The hemolymph of the fifth instar larvae of the silkworm Bombyx mori contains a group of homologous proteins with a molecular weight of approximately 30 kDa, termed B. mori low molecular weight lipoproteins (Bmlps), which account for about 5% of the total plasma proteins. These so-called "30 K proteins" have been reported to be involved in the innate immune response and transportation of lipid and/or sugar.

Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1.

The methionine S-sulfoxide reductase MsrA catalyzes the reduction of methionine sulfoxide, a ubiquitous reaction depending on the thioredoxin system. To investigate interactions between MsrA and thioredoxin (Trx), we determined the crystal structures of yeast MsrA/Mxr1 in their reduced, oxidized, and Trx2-complexed forms, at 2.03, 1.

Structure of Hsp33/YOR391Cp from the yeast Saccharomyces cerevisiae.

Saccharomyces cerevisiae Hsp33/YOR391Cp is a member of the ThiI/DJ-1/PfpI superfamily. Hsp33 was overexpressed in Escherichia coli and its crystal structure was determined at 2.40 Å resolution.