Publications by authors named "Xiao Xiao Fan"

Reactive astrogliosis is a critical process in the development of ischemic stroke. However, the precise mechanism by which reactive astrogliosis changes the pathogenesis of ischemic stroke remains elusive. Sterile alpha and TIR motif-containing 1 protein (SARM1) plays a key role in axonal degeneration and is involved in different cell death programs that regulate neuronal survival.

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Objective: To evaluate the clinical effectiveness of vacuum sealing drainage (VSD) in the treatment of severe scrotal infectious diseases and to summarize the practical experience obtained during its implementation.

Methods: Clinical data from 9 patients with severe scrotal infectious diseases were compiled. All patients underwent debridement assisted by a VSD device in addition to conventional treatment measures.

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Saussurea lappa originates in India, and now mainly grow in Yunnan, Sichuan and other places in China. It is one of the commonly used traditional herbal medicines in Tibet and other minority regions, with effects in regulating qi to relieve pain and invigo-rating spleen to promote food. It has been used in clinic for gastrointestinal diseases, such as Qi stagnation syndrome of spleen and stomach, diarrhea and tenesmus.

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Celastrol exhibits anticancer activity and has a number of potential molecular targets. Among them, the proteasome has attracted particular attention. Although celastrol inhibits multiple myeloma (MM) cell proliferation, the induction of proteasome-inhibitory activity by celastrol in MM cells at the cellular level and in tumors of mice bearing xenografts has not been confirmed.

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In this study, three GDI (gasoline direct injection) and one PFI (port fuel injection) light-duty gasoline vehicles were characterized for their particle emission (number concentration and size distributions). Two condensation particle counters (CPC) with different activation efficiencies (50% cut off diameter) were used. It was found that the number concentration of particles emitted by GDI gasoline vehicle was approximately one order of magnitude higher than that from PFI gasoline vehicle.

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