Publications by authors named "Xiao Qing Qi"

Article Synopsis
  • Scientists found that high hydrostatic pressure (HHP) makes it really hard for certain tiny organisms to divide their cells.
  • They studied a protein called FtsZ, which is super important for cell division, and discovered that FtsZ from deep-sea organisms can handle pressure way better than FtsZ from shallow water organisms.
  • By changing small parts of the FtsZ protein, they figured out which parts help it work well under high pressure, helping us understand how these tiny creatures survive in extreme conditions.
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  • Three psychrophilic bacteria strains (SQ149, SQ345, and S1-1) were isolated from deep-sea sediments in the South China Sea and showed high similarity to strain RZG4-3-1 based on 16S rRNA gene sequences (96.45 to 96.67%).
  • Phylogenetic and genetic analyses indicated that these strains form a distinct cluster and represent novel species, as their genetic markers fall below the species delimitation thresholds.
  • All strains are Gram-negative, rod-shaped, and contain specific fatty acids, respiratory quinones, and polar lipids, leading to their classification as new species within the genus, with proposed names for each strain.
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  • High hydrostatic pressure (HHP) plays a key role in regulating gene expression for microbes in deep-sea environments, with a focus on TMAO reductase which enhances pressure tolerance.
  • Researchers identified that the two-component regulator system, TorR and TorS, controls the expression of TMAO reductase (TorA) in response to HHP, distinguishing it from other known regulatory systems.
  • The study revealed that specific phosphorylation sites on TorS are crucial for functioning under HHP, indicating a complex signaling pathway that could help us better understand microbial adaptation to extreme pressures in the ocean.
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  • A new bacterium strain QS115 was discovered in deep-sea sediment from the South China Sea, showing strong genetic similarities to another strain, W43, but enough differences to classify it as a new species.
  • Strain QS115 is characterized as a Gram-negative, rod-shaped bacterium that thrives at low temperatures (10°C) and specific conditions (pH 7.5, 2% NaCl).
  • Key components of QS115 include unique fatty acids, a specific respiratory quinone, and distinct polar lipids, leading to its classification as a novel species in its genus with the proposed name sp. nov.
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Objective: The ultrasonic diagnosis of cervical and facial cystic masses, as well as cases of missed diagnosis and misdiagnosis, was examined, to improve the diagnosis of branchial cleft anomalies.

Methods: A retrospective analysis was conducted on 17 patients with branchial cleft cyst anomalies, including 11 males and 6 females, aged 12-53 years, with an average age of 33 ± 2 years, were unilateral single. All patients who underwent an ultrasound examination and image storage for retrospective analysis, and both longitudinal and transverse sections were scanned to observe the shape, size, boundary, peripheral relationship, and blood flow signal of the masses.

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  • Bioluminescence in deep-sea bacteria plays a key role in protecting against oxidative and UV stresses, but its impact on adaptation to high hydrostatic pressure (HHP) is not well understood.
  • A study compared a non-luminescent mutant strain of the bacterium ANT-2200 with its luminescent counterpart to assess pressure tolerance and oxidative stress response.
  • Findings indicated that bioluminescence acts as a crucial antioxidant system, helping bacteria adapt to the extreme deep-sea environment by managing oxidative stress from HHP.
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  • Deep-sea microorganisms adapt to high hydrostatic pressure through modifications in their respiratory components, but their ATP production strategies are less understood.
  • The study focused on the deep-sea bacterium SS9, revealing that it shows better growth and ATP production in minimal glucose medium compared to a complex medium under varying pressure conditions.
  • Researchers discovered that SS9 has two ATPase systems, with ATPase-I dominating in complex medium and ATPase-II being more prominent in minimal medium, indicating a functional relationship between these systems when under pressure.
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  • A new moderately thermophilic heterotrophic bacterium, strain 143-21, was isolated from a deep-sea hydrothermal vent at a depth of 2,440 m and is proposed as a novel species within its genus.
  • Phylogenetic and genomic analyses showed close relationships to similar bacteria, with 16S rRNA sequence similarities of around 96%.
  • Strain 143-21 grows optimally at temperatures of 50°C and pH 7.0, utilizes various sugars and amino acids, and produces fermentation products like acetate, while exhibiting unique fatty acids and polar lipids.
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Gilvimarinus sp. DA14, a putative new species isolated from mangrove sediment in the South China Sea (Beihai, Guangxi province), is an aerobic and heterotrophic agar degrading bacterium. Here, we present the complete genome sequence of strain DA14, which comprises 3.

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Crassaminicella sp. 143-21, a putative new species isolated from deep-sea hydrothermal vent chimney on the Central Indian Ridge (CIR), is an anaerobic, thermophilic and rod-shaped bacterium belonging to the family Clostridiaceae. In this study, we present the complete genome sequence of strain 143-21, comprising 2,756,133 bp with a G + C content of 31.

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  • Deep-sea hydrothermal vents, traditionally known for their chemosynthetic ecosystems, also potentially support phototrophic populations due to emitted light that may drive photosynthesis.
  • Metagenomic analyses of samples from the Southwest Indian Ridge revealed widespread distribution of phototrophic bacteria, including known chlorophototrophs, and highlighted the presence of complete chlorophyll biosynthetic pathways.
  • The findings suggest that geothermal vent light could provide energy that enhances the competitive advantage of phototrophs, supporting the idea of the ocean as a diverse microorganism seed bank.
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A novel moderately thermophilic, anaerobic, heterotrophic bacterium (strain SY095) was isolated from a hydrothermal vent chimney located on the Southwest Indian Ridge at a depth of 2730 m. Cells were Gram-stain-positive, motile, straight to slightly curved rods forming terminal endospores. SY095 was grown at 45-60 °C (optimum 50-55 °C), pH 6.

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A hyperthermophilic, strictly anaerobic archaeon, designated strain SY113, was isolated from a deep-sea hydrothermal vent chimney on the Southwest Indian Ridge at a water depth of 2770 m. Enrichment and isolation of strain SY113 were performed at 85 °C at 0.1 MPa.

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Hadal trenches are the deepest but underexplored ecosystems on the Earth. Inhabiting the trench bottom is a group of micro-organisms termed obligate piezophiles that grow exclusively under high hydrostatic pressures (HHP). To reveal the genetic and physiological characteristics of their peculiar lifestyles and microbial adaptation to extreme high pressures, we sequenced the complete genome of the obligately piezophilic bacterium DB21MT-5 isolated from the deepest oceanic sediment at the Challenger Deep, Mariana Trench.

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The purpose of this study was to evaluate the role of 2-D speckle tracking imaging in assessing left ventricular diastolic function in patients with connective tissue disease (CTD). A total of 98 CTD patients and 32 healthy controls were prospectively recruited. Early (E) and late (A) diastolic velocities of the transmitral flow were measured by pulsed Doppler echocardiography.

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Crassaminicella sp. strain SY095 is an anaerobic mesophilic marine bacterium that was recently isolated from a deep-sea hydrothermal vent on the Southwest Indian Ridge. Here, we present the complete genome sequence of strain SY095.

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species are widely distributed in marine environments, from the shallow coasts to the deepest sea bottom. Most species possess two isoforms of periplasmic nitrate reductases (NAP-α and NAP-β) and are able to generate energy through nitrate reduction. However, the contributions of the two NAP systems to bacterial deep-sea adaptation remain unclear.

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High hydrostatic pressure (HHP) exerts severe effects on cellular processes including impaired cell division, abolished motility and affected enzymatic activities. Transcriptomic and proteomic analyses showed that bacteria switch the expression of genes involved in multiple energy metabolism pathways to cope with HHP. We sought evidence of a changing bacterial metabolism by supplying appropriate substrates that might have beneficial effects on the bacterial lifestyle at elevated pressure.

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Background: The origin and heterogeneity of hepatic progenitor cells (HPCs) remain unclear. This study aimed to investigate the involvement of epithelial-mesenchymal transition (EMT) in the histogenesis of HPCs.

Methods: Surgical liver specimens from patients with HBV-related hepatitis and cirrhosis were investigated with double immunofluorescence labeling to detect antigens associated with HPCs and EMT.

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Background: The clear cell/signet-ring cell variant of cutaneous squamous cell carcinoma (cSCC) is extremely rare. Its carcinogenesis has consistently been linked to ultraviolet radiation and HPV in the literature. However, there is little definite information about the contribution of diabetes mellitus (DM) to cSCC.

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Metastasis, a cascade of events beginning with epithelial-to-mesenchymal transition (EMT), is the main cause of cancer-related mortality. EMT endows circulating cancer cells (CTCs) with invasive and anti-apoptotic properties. These transitioning cells leave the primary tumor site and travel through the circulation to populate remote organs, even prior to the onset of clinical symptoms.

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