Publications by authors named "Xiao Nan Gu"

Soil transmitted helminths (STHs) burden was enormous in China several decades ago, however, rigorous control efforts have been successful with appreciable reduction in diseases burden. Here, we assessed provincial-level data derived from cross sectional surveys, executed in 1989, 2002 and 2014, on the prevalence of STHs among populations in Jiangxi province, China. This study, also, reported STHs integrated control intervention aimed at reducing STHs transmission and worm burden among population at county-level.

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Objective: To grasp the status of snail-infested environments in schistosomiasis endemic areas of Jiangxi Province, and establish the spatial database of snail-infested environments with the administrative village as the unit.

Methods: The spatial and temporal distributions of the historical snail environments, existing snail environments, and suspicious snail-infested environments were analyzed by the historical data review and field investigations.

Results: The distribution of snail-infested environments in Jiangxi Province included two popular types of lakeshore and hills.

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Objective: To evaluate the role of new strategy in the transmission control of schistosomiasis in Poyang Lake region.

Methods: The information and epidemic data of schistosomiasis control were collected and analyzed in Poyang Lake region from 2005 to 2016.

Results: After eleven years of carrying out the new strategy, thirteen counties achieved the objective of transmission control in Poyang Lake region.

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Alpine treelines represent one of the most distinct vegetation boundaries between canopy closed montane forest and treeless alpine vegetation. This transitional ecotone is highly sensitive to global and regional climate change and is considered as an ideal indicator of such changes. Treeline studies have evolved from morphological description to various hypotheses of treeline formation.

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Objective: To evaluate the effect of schistosomiasis control strategy with emphasis on infection source control in the Yongxiu County promotion zone of Poyang Lake region.

Methods: The Wucheng Township of Yongxiu County was selected as the observation site, and the effect of the comprehensive control strategy was evaluated by using the method of field surveys combined with retrospective investigations.

Results: In 2010, there were 17 persons whose stool tests for schistosome infection were positive, and the number of calculated schistosomiasis patients was 2,331.

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Article Synopsis
  • This study analyzes the prevalence and control of schistosomiasis in Jiangxi Province from 2002 to 2012, noting significant control achievements over the decade.
  • The number of counties achieving transmission interruption increased, and infections in both humans and cattle decreased notably, indicating effective control measures.
  • By 2008, Jiangxi met criteria for endemic control, with stable low levels of infection and decreased snail populations contributing to the control of the disease.
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Article Synopsis
  • The study aimed to track water body infections of schistosomiasis using sentinel mice across various counties in China.
  • A total of 3,283 sentinel mice were used in 72 locations, with only 33 found to be infected, indicating a low overall infection rate of 1.08%.
  • Although the area of schistosomiasis risk has decreased since 2010, certain regions still remain high-risk for the disease.
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Objective: To investigate the changing rules of schistosomiasis endemic situation before and after reaching the criteria of schistosomiasis transmission controlled or interrupted in hilly endemic areas of Jiangxi Province, so as to provide the evidence for reformulating the criteria of schistosomiasis control and eradication in the future.

Methods: In the hilly areas of schistosomiasis endemic in Jiangxi Province, 2 counties where the transmission has been interrupted and 1 county where the transmission has been controlled were selected and investigated with the retrospective research method. The endemic detailed data were collected and recorded 10 years before reaching the criteria of transmission interrupted/controlled, and several years after reaching the criteria (ending in 2008), and then a database was established.

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Article Synopsis
  • The study investigates how the Three Gorges Project has altered the hydrological regime of Poyang Lake between 2002 and 2012 and its effect on schistosomiasis prevalence nearby.
  • Results show that after the project, water levels in Poyang Lake were lower throughout the year, leading to a significant decrease in schistosomiasis infection rates among humans (92.65%) and bovines (76.37%), as well as a 94.21% reduction in Oncomelania snail populations.
  • The findings indicate that the changed water conditions contributed to lower snail densities and reduced schistosomiasis prevalence, complemented by enhanced control efforts in the area.
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Objective: To evaluate the situation of realizing schistosomiasis transmission control in Jiangxi Province.

Methods: The situation of reaching the criteria of schistosomiasis transmission control was evaluated by using the method of field surveys combined with retrospective investigations.

Results: The schistosome infection in human was kept at a stable low level, and the infection rate in residents was below 1% in 90.

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Objective: To investigate the impact of the Water Conservancy Project of Poyang Lake after operation on Oncomelania hupensis snail habitats in 10 counties (cities or districts) around Poyang Lake.

Methods: The data of the distribution, numbers, areas, elevation and slope, etc. of snail infested marshlands on upstream of the project site in Poyang Lake were investigated and collected.

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Objective: To explore the approach and tool for surveillance and forecast of schistosomiasis, so as to provide scientific evidence for improving the sensitivity of the surveillance and forecast system of schistosomiasis.

Methods: Two field detections were carried out in June and September by using the determination of sentinel mice in key high-risk water regions of 7 provinces of Hunan, Hubei, Jiangxi, Anhui, Jiangsu, Yunnan and Sichuan, and the sentinel mice were raised in laboratory and dissected for observation of schistosome infections. The database regarding schisosome infections in key water regions of China was established, and the tempo-spatial distribution and environmental features of the national surveillance and forecast sites with positive sentinel mice were analyzed.

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Objective: To investigate risk factors for the development of advanced schistosomiasis.

Methods: The case-control study was designed with a match of 1:1 and 1:2. Healthy persons and chronic schistosomiasis patients were used as control.

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