Computed tomography texture analysis combined with preoperative clinical factors serve as a predictor of early efficacy of transcatheter arterial chemoembolization in hepatocellular carcinoma.

Aim: To investigate a pre-therapeutic radiomics nomogram to accurately predict hepatocellular carcinoma (HCC) lesion responses to transcatheter arterial chemoembolization (TACE).

Methods: This retrospective study from January 2012 to 2022 included 92 TACE-treated patients who underwent liver contrast-enhanced CT scan 7 days before treatment, having complete clinical information. We extracted quantitative texture parameters and clinical factors for the largest tumors on the baseline arterial and portal venous phase CT images.

Innovating Novel Online Social Spaces with Diverse Middle School Girls: Ideation and Collaboration in a Synchronous Virtual Design Workshop.

Leveraging social media as a domain of high relevance in the lives of most young adolescents, we led a synchronous virtual design workshop with 17 ethnically diverse, and geographically-dispersed middle school girls (aged 11-14) to co-create novel ICT experiences. Our participatory workshop centered on social media innovation, collaboration, and computational design. We present the culminating design ideas of novel online social spaces, focused on positive experiences for adolescent girls, produced in small-groups, and a thematic analysis of the idea generation and collaboration processes.

The role of parents, other adults, peers and informal learning communities in shaping positive social media use in adolesent girls.

Purpose: This study aims to introduce the concept of communities of social media practice where more experienced users provide guidance to female novice users, enacting a form of legitimate peripheral participation to "onboard" newcomers.

Design/methodology/approach: Through surveys with 968 early adolescents (average age was 13), the authors quantitatively explored sources and types of guidance for young social media users, popularity of conversation themes related to this guidance and how these conversations are associated with positive social media engagement. The authors qualitatively documented a case study of how a summer workshop of 17 students promotes positive social media use through a community of practice.

Role of clinical data and multidetector computed tomography findings in acute superior mesenteric artery embolism.

Background: Superior mesenteric artery embolism (SMAE) has acute onset and fast progression, which seriously threatens the life of patients. Multidetector computed tomography (MDCT) is one of the most important diagnostic methods for SMAE, which plays an important role in the diagnosis and prognosis of SMAE.

Aim: To evaluate the value of combined clinical data and MDCT findings in the diagnosis of acute SMAE and predict the risk factors for SMAE-related death.

Aberrant brain functional connectome in patients with obstructive sleep apnea.

Objective: Obstructive sleep apnea (OSA) is accompanied by widespread abnormal spontaneous regional activity related to cognitive deficits. However, little is known about the topological properties of the functional brain connectome of patients with OSA. This study aimed to use the graph theory approaches to investigate the topological properties and functional connectivity (FC) of the functional connectome in patients with OSA, based on resting-state functional magnetic resonance imaging (rs-fMRI).

Disrupted small-world brain functional network topology in male patients with severe obstructive sleep apnea revealed by resting-state fMRI.

Purpose: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder that can damage cognitive function. However, the functional network organization remains poorly understood. The aim of this study was to investigate the topological properties of OSA patients using a graph theoretical analysis.

Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish.

Cis-stilbene combretastatin A-4 (CA-4) and a large group of its derivant compounds have been shown significant anti-angiogenesis activity. However the side effects even the toxicities of these chemicals were not evaluated adequately. The zebrafish model has become an important vertebrate model for evaluating drug effects.