Publications by authors named "Xiao L DU"
() is a significant foodborne pathogen and a common cause of intestinal diseases in both animals and humans. Our study investigated MLST, phenotypic antimicrobial resistance profiles, and resistance genes among isolates from human, animal and food. 186 isolates were obtained from nine provinces in China between 2013 and 2021.
View Article and Find Full Text PDFApplication of a core genome sequence typing (cgMLST) pipeline for surveillance of in China.
Front Cell Infect Microbiol
March 2023
Article Synopsis
- The text discusses a nosocomial bacterial pathogen responsible for antibiotic-associated diarrhea, highlighting the role of exotoxins and methods for genetic typing such as MLST and whole genome sequencing (WGS).
- A study analyzed 699 genome sequences of distinct strains to establish a core gene set and develop a core genome multilocus sequence typing (cgMLST) scheme for phylogenetic analysis.
- The findings categorized the bacterial isolates into five clades and successfully tracked an outbreak, suggesting a valuable surveillance system for this pathogen in China.
Article Synopsis
- A study was conducted in Shanghai to investigate the prevalence, genetic diversity, antibiotic resistance, and pathogenicity of strains isolated from food, as these strains have been recognized as emerging human pathogens associated with diarrhea worldwide.
- A total of 79 food isolates were analyzed, revealing eight different species, with most being hemolytic and showing antibiotic resistance; specifically, 11.4% were multidrug-resistant and 93.7% were resistant to cefazolin.
- The findings indicate that certain isolates are highly pathogenic, posing risks to public health, and emphasize the importance of monitoring food safety to improve prevention and treatment of diarrhea-related illnesses in China.
Cadmium (Cd), a widespread, severely toxic heavy metal, can cause serious reproductive toxicity in animals. However, the molecular pathways associated with Cd-induced effects remain unknown. In this study, we first cloned the vasa gene (Shvasa) and characterized the VASA protein (ShVASA) in Sinopotamon henanense.
View Article and Find Full Text PDFObjective: This study was performed to compare the genetic diversity, virulence, and antimicrobial resistance of strains isolated from patients and healthy individuals.
Methods: A total of 38 clinical strains and 19 strains from healthy individuals were isolated from the samples collected in Ma'anshan City, Anhui Province. Their taxonomy was investigated using concatenated - sequences, and their resistance to 12 antibiotics was evaluated.
Background: The aim of this study was to investigate the risk of symptomatic pulmonary embolism (PE) in patients with combined lower extremity deep vein thrombosis (DVT) and iliac vein compression syndrome (IVCS).
Methods: Between January 2011 and February 2014, 399 patients diagnosed with combined lower extremity DVT and IVCS at the Second Affiliated Hospital of Soochow University were included in this retrospective study. The odds of symptomatic PE versus combined lower extremity DVT and IVCS were assessed using logistic regression models.
A sensitive and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the determination of asperosaponin VI in beagle dog plasma using glycyrrhizic acid as the internal standard (IS). Plasma samples were simply pretreated with methanol for deproteinization. Chromatographic separation was performed on a Hedera ODS-2 column using mobile phase of methanol-10 mm ammonium acetate buffer solution containing 0.
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