Prediction of dual-phenotype hepatocellular carcinoma based on ultrasound and contrast enhanced ultrasound - a preliminary study.

Aims: To investigate the diagnostic value of ultrasound features with dual-phenotype hepatocellular carcinoma (DPHCC). Material and methods: A retrospective analysis was conducted on patients diagnosed with hepatocellular carcinoma (HCC) confirmed by pathology results from October 2016 to December 2023. Patients were categorized into DPHCC and non-DPHCC (NDPHCC) groups based on immunohistochemical findings.

[Cloning and function characterization of a UDP-rhamnose synthase from Dendrobium huoshanense].

UDP-rhamnose, which is synthesized under the catalysis by the rhamnose synthase(RHM), is an essential sugar donor for the synthesis of rhamnoside in plants. Based on the reported rhamnose synthase, this study screened one RHM gene(DhuRHM) from the localized gene database of Dendrobium huoshanense by sequence alignment. This gene was cloned, and then bioinformatics analysis and in vitro functional verification were carried out.

Application value of contrast-enhanced ultrasound in the preoperative evaluation of renal cell carcinoma histological classification and RENAL score.

Background: Renal cell carcinoma (RCC), the most common malignant renal tumor, is primarily treated by surgical resection, including radical nephrectomy (RN) and partial nephrectomy (PN). At present, the choice of surgery mainly depends on the comprehensive evaluation of patients' clinical data, including histological classification, such as clear cell renal cell carcinoma (ccRCC) and non-clear cell renal cell carcinoma (nccRCC), and RENAL (radius, exophytic/endophytic, nearness, anterior/posterior, and location) score. Compared with biopsy and contrast-enhanced computed tomography (CECT), contrast-enhanced ultrasound (CEUS) is safer and less invasive.

Experimental study on the translation behavior of an in-situ bubble pair in the ultrasonic field.

The dynamics of acoustic cavitation bubbles hold significant importance in ultrasonic cleaning, biomedicine, and chemistry. Utilizing an in-situ normal pressure bubble generation and observation system that was developed, this study examined the translational behavior of micrometer-scale normal pressure bubble pairs with initial radius ratio of 1:1 and 2:1 under ultrasonic field excitation. A velocity-distance curve was proposed to quantify the secondary Bjerknes forces during various interaction stages of the bubbles.

Specific Influences of Trap States with Distinct Spatial and Energetic Distributions on Ion Migration Dynamics in Metal Halide Perovskites.

Trap state engineering has been widely employed to manipulate the dynamics of ion migration in metal halide perovskites (MHPs), a crucial factor associated with the performance and stability of MHP-based devices. However, the specific roles of different trap states remain poorly understood due to their complicated spatial and energetics distributions. Herein, we propose a methodology for independently regulating the distributions of bulk shallow and surface deep trap states in MHPs.

Project-based learning as a catalyst for 21st-Century skills and student engagement in the math classroom.

Along with traditional academic knowledge, 21st-century skills are crucial for equipping students with a competitive future. Project-based learning (PBL) cultivates these competencies among learners as an instructional approach. This research aimed to construct and analyze a PBL framework designed to weave 21st-century skills into high school education.

Impact of the COVID-19 outbreak on the field of hematopoietic cell transplantation in the Asia-Pacific region: APBMT Activity Survey 2020/2021.

COVID-19 became a global pandemic in 2020 and significantly affected the activity of hematopoietic cell transplants (HCT) worldwide. Despite these challenges, a total of 28,793 transplants, including 18,518 allogeneic and 10,275 autologous transplants, were performed in 719 facilities in 2020 in the Asia-Pacific (AP) region. This represented a 5.

5G-based collaborative trajectory following modeling and enhancement in connected and automated airspace environment.

In an emerging trajectory-based operation (TBO) environment within the advanced autonomous airspace, traffic operation along reference trajectories can function as trajectory-following mechanisms. However, 5G-based following dynamics still remain underexplored, limiting further utilization of lower-latency 5G technology other than data links. This limitation affects air traffic stability when encountering disturbance, preventing autonomous airspeed adjustment, and safe separation without air traffic controller interventions.

Exploring the natural-socioeconomic driving and response mechanisms of ecosystem services interactions to optimize ecosystem management: A case study in the Yarlung Zangbo River Basin.

Revealing the complex interactions between ecosystem services (ESs) and their underlying mechanisms is a prerequisite for formulating sustainable ecological management strategies. However, few studies have conducted a comprehensive analysis of the driving and response mechanisms of ESs interactions. Therefore, this study established an integrated framework to first quantify the interactions between ESs, then identify their dominant natural-socioeconomic drivers, explore their spatial non-stationary responses, and ultimately propose corresponding strategies to optimize ecosystem management.

Independent and joint effect of central and brachial SBP on incident stroke in hypertensive adults.

Objective: It is unclear whether central SBP (cSBP) is an independent predictor of stroke above and beyond brachial SBP (bSBP). This study aimed to investigate the difference between cSBP and bSBP in predicting first stroke and the joint effect of cSBP and bSBP on the risk of first stroke in hypertensive adults.

Methods: A total of 8122 hypertensive adults without stroke history were included in this study.

Association between intergenerational contact and cognitive function in middle-aged and older Chinese adults: The mediating role of functional disability and depressive symptoms.

Background: Previous studies have documented the impact of intergenerational contact on cognitive function in Chinese adults, however, few have focused on the possible mediating pathways. This study aimed to test a hypothetical model in which functional disability and depressive symptoms mediate the association between intergenerational contact and cognitive function.

Methods: This longitudinal study included data of 3666 participants aged 45 years or older (mean age: 60.

Association between Weight-Adjusted Waist Index and Depression in NAFLD: the modulating roles of sex and BMI.

Background: The Weight-Adjusted Waist Index (WWI) is a novel indicator of obesity that accurately reflects body composition. However, the association between WWI and depression in patients with non-alcoholic fatty liver disease (NAFLD) remains unclear. This study aims to explore this relationship through a nationally representative cross-sectional analysis.

Screening of pathologically significant diagnostic biomarkers in tears of thyroid eye disease based on bioinformatic analysis and machine learning.

Background: Lacrimal gland enlargement is a common pathological change in patients with thyroid eye disease (TED). Tear fluid has emerged as a new source of diagnostic biomarkers, but tear-based diagnostic biomarkers for TED with high efficacy are still lacking.

Objective: We aim to investigate genes associated with TED-associated lacrimal gland lesions.

Vehicular Mini-LED backlight display inspection based on residual global context mechanism.

Mini-LED backlight has emerged as a promising technology for high performance LCDs, yet the massive detection of dead pixels and precise LEDs placement are constrained by the miniature scale of the Mini-LEDs. The high-resolution network (Hrnet) with mixed dilated convolution and dense upsampling convolution (MDC-DUC) module and a residual global context attention (RGCA) module has been proposed to detect the quality of vehicular Mini-LED backlights. The proposed model outperforms the baseline networks of Unet, Pspnet, Deeplabv3+, and Hrnet, with a mean intersection over union (Miou) of 86.

Zinc and melatonin mediated antimicrobial, anti-inflammatory, and antioxidant coatings accelerate bone defect repair.

Inflammation and bacterial infection are important causes of implant failure, and the development of multifunctional titanium surfaces to address these issues is an effective means of treating infected bone defects. In this study, polyphenols (EGCG) and Zn were first loaded onto the titanium surface to construct an EGCG/Zn polyphenol metal network coating. Then melatonin (MT) was loaded into the EGCG/Zn network structure to prepare the EGCG/Zn/MT composite coating.

Impact of rifaximin on cirrhosis complications and gastric microbiota in patients with gastroesophageal variceal bleeding: A pilot randomized controlled trial.

Objectives: The application of rifaximin, a non-absorbable antibiotic, in hepatic encephalopathy (HE) has been well established; however, its effect on other complications in cirrhotic patients with previous gastroesophageal variceal bleeding (GEVB) remains unclear. Therefore, we performed a pilot randomized controlled trial aiming to evaluate the impact of rifaximin on cirrhosis-related complications and changes in gastric microbiota.

Methods: Eighty cirrhotic patients who received prophylactic endoscopic treatment for variceal rebleeding were randomly assigned to the control or rifaximin treatment group (rifaximin 400 mg twice daily for 8 weeks).

Establishment of a nomogram for potential prediction of lung metastasis in patients with primary limb bone tumors: a study based on the SEER database.

Background: The prognosis of lung metastasis in primary limb bone tumors represents a pivotal yet challenging aspect of oncological management. Despite advancements in diagnostic modalities, the predictive accuracy for metastatic spread remains suboptimal. This study aims to bridge this gap by leveraging the Surveillance, Epidemiology, and End Results (SEER) database to construct a nomogram that forecasts the risk of lung metastasis, thereby enhancing clinical decision-making processes.

Effects of spraying cycocel and delaying nitrogen application on lodging resistance and yield formation of winter wheat.

We conducted a 3-year (2017-2020) field experiment in the wheat base of Jinzhong Agricultural Hi-tech Industries Demonstration Zone, aiming to determine the measures of nitrogen topdressing and the regulatory effect of cycocel in spring to increase wheat yield. Four nitrogen topdressing dates were set up under the condition of cycocel spraying and control (CK) during the rising period: 10 days (D10), 20 days (D20), 30 days (D30), and 40 days (D40) after regreening stage, to analyze the impact of different N topdressing dates on winter wheat yield and the regulation effect of cycocel on stem characteristics, lignin content and related synthetase activities. The results showed that compared to other nitrogen topdressing dates, D30 increased spike number by 1.