Maleic acid and malonic acid reduced the pathogenicity of Sclerotinia sclerotiorum by inhibiting mycelial growth, sclerotia formation and virulence factors.

Sclerotinia sclerotiorum is a necrotrophic plant pathogenic fungus with broad distribution and host range. Bioactive compounds derived from plant extracts have been proven to be effective in controlling S. sclerotiorum.

Integrative analysis reveals marker genes for intestinal mucosa barrier repairing in clinical patients.

This study aims to identify biomarkers of intestinal repair and provide potential therapeutic clues for improving functional recovery and prognostic performance after intestinal inflammation or injury. Here, we conducted a large-scale screening of multiple transcriptomic and scRNA-seq datasets of patients with inflammatory bowel disease (IBD), and identified 10 marker genes that potentially contribute to intestinal barrier repairing: and . Analysis of a published scRNA-seq dataset revealed that expression of these healing markers were specific to absorptive cell types in intestinal epithelium.

Cystathionine gamma-lyase (Cth) induces efferocytosis in macrophages via ERK1/2 to modulate intestinal barrier repair.

Background: The inflammatory response induced by intestinal ischaemia‒reperfusion injury (I/R) is closely associated with infectious complications and mortality in critically ill patients, and the timely and effective clearance of apoptotic cells is an important part of reducing the inflammatory response. Studies have shown that the efferocytosis by phagocytes plays an important role. Recently, studies using small intestine organoid models showed that macrophage efferocytosis could promote the repair capacity of the intestinal epithelium.

Risk factors for postpartum depression: An evidence-based systematic review of systematic reviews and meta-analyses.

Purpose: Postpartum depression (PPD) is the most common psychiatric condition after childbirth which not only effects the mother's health, but also might have impact on child's development and parenting behaviors. Because the etiology of PPD has not been fully cleared, the efforts towards identification of risk factors are crucial for both the children and mother's health.

Method: PubMed, EMBASE and PsycINFO databases were searched since inception until July 2019 to collect data about the risk factors of PPD and only systematic review and meta-analysis can be included.

Sample entropy and surrogate data analysis for Alzheimer's disease.

Alzheimer's disease (AD) is a neurological degenerative disease, which is mainly char-acterized by the memory loss. As electroencephalogram (EEG) device is relatively cheap, portable and non-invasive, it has been widely used in AD-related studies. We proposed a method to detect the differences between healthy subjects and AD patients, which combines classical sample entropy (Sam-pEn) and surrogate data method.

Heterogeneity of nutrition care procedures in nutrition guidelines for cancer patients.

Objectives: The aim of this study was to systematically assess the nutrition care procedures in nutrition guidelines for cancer patients and identify gaps limiting evidence-based practise.

Methods: A systematic search of databases and websites was conducted to identify nutrition guidelines for cancer patients. The quality of the eligible guidelines was evaluated by using the Appraisal of Guidelines for Research and Evaluation (AGREE II).

Dissolved organic matter derived from rape straw pretreated with selenium in soil improves the inhibition of Sclerotinia sclerotiorum growth.

Sclerotinia sclerotiorum (S. sclerotiorum) is a soil-borne pathogen with broad host range. Dissolved organic matter (DOM) plays a vital role in regulating microbial activity in soil.

Recognition of the toxicity of aristolochic acid.

What Is Known And Objective: Aristolochic acid (AA) is an abundant compound in Aristolochia plants and various natural herbs. In the 1990s, a slimming formula used in Belgium that contains Aristolochia fangchi was reported to cause kidney damage and bladder cancer, and aristolochic acid nephropathy (AAN) is now well recognized worldwide. In October 2017, researchers reported an AA signature that is closely associated with hepatocellular carcinoma (HCC) worldwide.

Can Selenium and Molybdenum Restrain Cadmium Toxicity to Pollen Grains in ?

Cadmium (Cd) is highly toxic, even at very low concentrations, to both animals and plants. Pollen is extremely sensitive to heavy metal pollutants; however, less attention has been paid to the protection of this vital part under heavy metal stress. A pot experiment was designed to investigate the effect of foliar application of Se (1 mg/L) and Mo (0.

[Effects of Wastewater Nitrogen Concentrations and NH/NO on Nitrogen Removal Ability and the Nitrogen Component of (Vell.) Verdc].

Solution culture experiments were conducted to investigate the effect of wastewater nitrogen levels and NH/NO on nitrogen removal ability and the nitrogen component of . Experiments with three nitrogen levels and NH/NO were set up as follows:20, 100, and 200 mg·Land NH/NO 1:0, 0.5:0.

Uptake, transport and distribution of molybdenum in two oilseed rape (Brassica napus L.) cultivars under different nitrate/ammonium ratios.

Objectives: To investigate the effects of different nitrate sources on the uptake, transport, and distribution of molybdenum (Mo) between two oilseed rape (Brassica napus L.) cultivars, L0917 and ZS11.

Methods: A hydroponic culture experiment was conducted with four nitrate/ammonium (NO:NH) ratios (14:1, 9:6, 7.

[Effect of Wastewater Nitrogen Concentrations on Nitrogen Removal Ability of ].

, which is an important plant for constructed wetlands, has powerful purification ability for wastewater, however, the relationship between nitrogen removal ability of and wastewater nitrogen concentrations is still unclear. In this study, pot culture experiment was conducted to investigate the effect of wastewater nitrogen levels on nitrogen removal ability of . 7 nitrogen levels were set up as following:2, 5, 10, 20, 100, 200, 400 mg·L.

Abnormal intrinsic brain activity in amnestic mild cognitive impairment revealed by amplitude of low-frequency fluctuation: a resting-state functional magnetic resonance imaging study.

Background: Previous studies have shown that brain functional activity in the resting state is impaired in Alzheimer's disease (AD) patients. However, alterations in intrinsic brain activity patterns in mild cognitive impairment (MCI) patients are poorly understood. This study aimed to explore the differences in regional intrinsic activities throughout the whole brain between aMCI patients and controls.

[In vivo labeling of rat neural progenitor cells in subventricular zone with superparamagnetic iron oxide for tracking of magnetic resonance imaging].

Objective: To explore the feasibility of in vivo labeling of adult rat neural progenitor cells (NPCs) in subventricular zone (SVZ) with superparamagnetic iron oxide particles (SPIOs) for tracking of magnetic resonance imaging (MRI).

Methods: A total of 7 SD rats were stereotactically injected with 3 µl SPIOs (7 mg Fe/ml) into anterior horn of right lateral ventricle and then 5-bromo-2'-deoxyuridine (BrdU) was injected intraperitoneally once daily for 1 week. MRI was performed at 1, 3, 7 and 14 days post-injection.

Dietary intake and risk for reflux esophagitis: a case-control study.

Background. Specific dietary components have been associated with gastroesophageal reflux disease (GERD) in Europe and the United States. However, the relationship between dietary components and GERD in Chinese still remains unclear.

[Values of ocular hemodynamics and serum endothelin-1 in the early diagnosis of diabetic retinopathy].

Objective: To evaluate the values of ocular hemodynamics and serum endothelin-1 (ET-1) in the early diagnosis of diabetic retinopathy (DRP).

Methods: A total of 85 DRP patients were examined by ophthalmoscope and fluorescein angiography and divided into 3 groups: no obvious retinopathy (n = 20), non-proliferative diabetic retinopathy (n = 35) and proliferative diabetic retinopathy (n = 30). Control group included 15 healthy volunteers.

[Small-worldness of functional networks in Alzheimer's disease].

Objective: To construct the functional networks of human brains by resting-state functional magnetic resonance imaging (fMRI) and examine whether or not the small-world property of functional brain networks changes in patients with Alzheimer disease (AD).

Methods: A total of 33 AD patients and 20 healthy old volunteers were recruited. Their cognitive functions were evaluated by the mini-mental state examination (MMSE) and Mattis dementia rating scale (DRS).

CT presentations of colorectal cancer with chronic schistosomiasis: A comparative study with pathological findings.

Objective: To clarify pathological basis of computed tomography (CT) presentations of colorectal cancer (CRC) with schistosomiasis for the purpose of improving the accuracy of CT diagnosis and differential diagnosis of the condition.

Materials And Methods: 130 patients (87 male and 43 female; age range 49-86 years, mean 71.1) were selected whose diagnoses were pathologically confirmed as CRC with schistosomiasis.

Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis.

Background: Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer's disease (AD) patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals.

Microcalorimetric studies of perchlorate on heat production by hepatocytes and mitochondria isolated from Carassius auratus.

As a new threat to environment all through the world, perchlorate (ClO(4)(-)) was predominantly a thyrotoxin, and its toxic manifestations in non-thyroid were also documented. However, little is known about the effects of ClO(4)(-) on cell and organelle. Therefore, the present study was designed to investigate the effects of ClO(4)(-) on hepatocytes and mitochondria isolated from Carassius auratus from the direct viewpoint of energy by using the microcalorimetric method.

[Central mechanism of electric-acupuncture at Zusanli (ST36) for gastric mucous membrane protection with FMRI].

Objective: To explore the central mechanism of acupuncture in protecting gastric mucous membrane by a composite analysis of gastric mucous membrane related indices in peripheral blood and functional MRI (fMRI) signal changes after electric-acupuncturing Zusanli (ST36) acupoint.

Methods: Sixteen healthy adult volunteers were divided into true acupoint group (A) and sham acupoint group (B). Zusanli acupoint was used for Group A.

Brain processing of visceral sensation upon esophageal chemical stimulation in different types of GERD.

We designed to investigate the cortical response to esophageal acid exposure in different types of gastroesophageal reflux disease (GERD) by functional magnetic resonance imaging (fMRI). Fifteen healthy volunteers, 13 with reflux esophagitis (RE), 12 with non-erosive reflux disease with abnormal acid reflux (NERD+) and nine with non-erosive reflux disease with normal acid reflux (NERD-) received intraesophageal perfusion with isotonic saline followed by 0.1 N hydrochloric acid.