. Non-primary radiation doses to normal tissues from proton therapy may be associated with an increased risk of secondary malignancies, particularly in long-term survivors. Thus, a systematic method to evaluate if the dose level of non-primary radiation meets the IEC standard requirements is needed.
View Article and Find Full Text PDFBackground: Increased homocysteine levels are associated with the risk of cardiovascular disease (CVD) and death. However, their prevention has not been effective in decreasing CVD risk. This study investigated the individual and combined associations of hyperhomocysteinemia and hypertension with incident CVD events and all-cause death in the Chinese elderly population without a history of CVD.
View Article and Find Full Text PDFComb Chem High Throughput Screen
March 2022
Aim: It has been reported that glial cells are involved in Alzheimer's disease (AD). In our previous research, Scutellaria barbata flavonoids (SBFs) were found to protect the AD-like rats from neuronal disorder and memory impairment; however, the effect of SBFs on the glial cells disorder in AD-like rats has been less studied. The effects of SBFs on astrocytes (ASs), microglial cells (MGs), and oligodendrocytes (Ols), as well as heat shock protein 70 (Hsp70) and apolipoprotein E (ApoE), were investigated in the present study.
View Article and Find Full Text PDFBiomed Environ Sci
September 2017
Objective: To evaluate the clinical effects of over 5 year follow up of unilateral pedicle screw fixation with transforaminal lumbar interbody fusion(TLIF) in treating lumbar degenerative diseases.
Methods: The clinical data of 24 patients with lumbar degenerative disease underwent unilateral pedicle screw fixation with transforaminal lumbar interbody fusion from March 2007 to October 2009, were retrospectively analyzed. There were 13 males and 11 females, aged from 34 to 68 years old with an average of 52 years.
Primary Objective: To study the effect of flavonoids isolated from aerial parts of Scutellaria baicalensis Georgi (SSF) on cerebral damage induced by okadaic acid (OA) in rats.
Methods And Procedures: OA was microinjected into the right lateral ventricle of male rats at a dose of 200 ng kg(-1) twice with a 3-day interval between injections to establish a model of Alzheimer's-disease-like cerebral damage. Neuronal morphology was observed with thionin staining and the expressions of glial fibrillary acidic protein (GFAP) and β-amyloid peptide 1-40 (Aβ1-40) were monitored via immunohistochemistry.
Objective: To discuss the correlation of tongue manifestation with the site of cerebral infarction in patients with acute cerebral infarction.
Methods: From March 2008 to February 2009, 200 cases of hospitalized patients with first unilateral cerebral infarction were chosen in the Department of Neurology, Xuanwu Hospital. The correlation of different tongue color, fur texture, fur color with the site of cerebral infarction was analyzed.
Objective: To discuss the relationship between tongue manifestation and the degree of neurological impairment in the patients with acute cerebral infarction.
Methods: Two hundred patients with first unilateral cerebral infarction were recruited. The relationship between different tongue manifestation and National Institute of Health Stroke Scale (NIHSS) were analyzed.
Objective: To evaluate the value of wavelet index (WLI) in general anesthesia through a comparison of WLI with bispectral index (BIS).
Methods: A total of 53 patients scheduled for elective surgery with ASA (American Society of Anesthesiologists) I-II were selected to undergo general anesthesia. The monitoring probes of BIS, WLI and muscle relaxation were connected in awaking patients.
Zhonghua Liu Xing Bing Xue Za Zhi
October 2011
Objective: To study the mortality and risk of death on dementia among ageing population.
Methods: A random sample including 2788 elderly residents was studied. Dementia was diagnosed under the two-phase procedure in 1997.
Zhonghua Liu Xing Bing Xue Za Zhi
November 2010
Objective: To study the incidence of dementia and its risk factors among the elderly living in the community of Beijing.
Methods: A sample of 2788 elderly residents from Beijing were investigated regarding the incidence of dementia which was diagnosed using two-stage method in 1997. In the first stage, questionnaire was filled, including MMSE checked up.
Sichuan Da Xue Xue Bao Yi Xue Ban
January 2010
Objective: To explore the protective mechanism of BuYangHuanWu recipe on neurofunction in gerbils with cerebral ischemia- reperfusion.
Methods: Gerbils (n = 48) were divided randomly into three groups: animal model group, BuYangHuanWu recipe group, and sham control group. The animal model of cerebral ischemia was established using bilateral common carotid artery occlusion followed by unclamp 45 min after occlusion.
Zhonghua Jie He He Hu Xi Za Zhi
November 2009
Objective: To compare different Mycobacterium tuberculosis antigens in enzyme-linked immunospot assay (ELISPOT) for the auxiliary diagnosis of active tuberculosis.
Methods: The peripheral blood mononuclear cells (PBMC) from patients with tuberculosis and controls were co-cultured with the following antigens: purified protein derivative (PPD), early secretory antigenic target-6 (ESAT-6) and early secretory antigenic target-6/culture filtrate protein-10 fusion protein (ESAT-6/CFP-10). Spot forming cells (SFC) were enumerated by ELISPOT.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
August 2009
Objective: To compare enzyme-linked immunospot assay (ELISPOT) and tuberculin skin test (TST) and explore their roles in the auxiliary diagnosis of initial pulmonary tuberculosis.
Methods: Totally 123 patients with initial pulmonary tuberculosis (tuberculosis group) and 102 patients with non-tuberculosis pulmonary disease (control group) were enrolled. The peripheral blood mononuclear cells of all participants were co-cultured with early secretiny antigen target-6/culture filtrate protein-10 fusion protein (ESAT-6/CFP-10), and spot forming cells (SFCs) were enumerated by ELISPOT (ESAT-6/CFP-10-ELISPOT).
Zhonghua Liu Xing Bing Xue Za Zhi
February 2008
Objective: In order to explore the risk factors of geriatric depression, a longitudinal follow-up study was conducted on elderly population living in the community so as to provide evidence for the development of depression prevention and control.
Methods: A sampled population consisting 2506 elderly was selected from urban and rural communities in Beijing, using well-established sampling techniques as cluster, stratification and random selection. Data was collected by trained staff members, using standard survey instruments in 2000 and 2004.
Zhonghua Xin Xue Guan Bing Za Zhi
October 2007
Objective: To observe the relationship between coronary and carotid/cerebral atherosclerotic stenosis.
Methods: Carotid/aortocranial angiography and coronary angiography were performed in 34 CAD patients complicated with symptomatic cerebral ischemia. Patients were divided into 3 subgroups according to the extent of arterial stenosis determined by angiography.
Zhonghua Liu Xing Bing Xue Za Zhi
March 2007
Objective: We followed a group of community residents above 60 years old to investigate how isolated systolic hypertension (ISH) could influence the prognosis in the long run among the elderly.
Methods: A selected sample of 60 year olds and over from the Beijing residential communities was randomized ascertained to a longitudinal study. Baseline data was collected in 1993 and 11 years later in 2004, the all-cause death, mortality of cardiovascular and cerebrovascular diseases were observed and analyzed.
Zhonghua Liu Xing Bing Xue Za Zhi
October 2005
Objective: To describe the prevalence and disability of stroke as well as the stroke-related diseases among elderly in urban and rural regions of Beijing.
Methods: In 2002, three communities were selected from urban, suburb and rural regions from Beijing areas, respectively. Twenty percent of the elderly were randomly selected from three communities.
Objective: To study the predictive effects of some health status indicators to deaths in the elderly population.
Methods: In 1992, a cohort of 3257 people older than 55 years old was formed from Beijing urban and suburb area. Demographic and information of activity of daily living (ADL), self-rated health (SRH), chronic diseases history and other related variables were collected at baseline survey in 1992.
Shanghai Kou Qiang Yi Xue
December 2003
Objective: To clarify the occurrence and distribution of the fusion of deciduous teeth in Shenyang.
Methods: By using cross-sectional study, 4286 children were examined, who aged from 2 to 6 years in 37 kindergartens.
Results: Of 4286 children investigated, fusion of the deciduous teeth were detected in 65 children (1.
Objective: To study the relationship between self-rated health (SRH) and prevalence of chronic diseases, and all-cause mortality in the elderly population.
Methods: In 1992, a cohort of 3257 people > or = 55 years old was selected from Beijing, the information of SRH and other related variables were collected from 3 157 subjects at the baseline survey. Three follow-up surveys were conducted in 1994, 1997 and 2000, respectively.
Vortex core dynamics is studied in the Brusselator both near to and far from the Hopf bifurcation line for random and pair initial conditions. Extensive simulations are carried out for a pair of counter-rotating vortices close to the Hopf bifurcation line. Provided the vortices are not so far apart that wave-front annihilation produces strong gradients between their centers, the simulation results compare favorably with theories based on the complex Ginzburg-Landau equation.
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