Publications by authors named "Xiao Feng Mei"
Article Synopsis
- The study investigates the role of urinary proteins and hypercoagulability in the development of IgA vasculitis (IgAV) by comparing the urinary biomarkers of healthy children and those with IgAV.
- Using advanced techniques, researchers identified 772 proteins with significant differences, with key findings highlighting the involvement of proteins like thrombin and macrophage migration inhibitory factor (MIF) in inflammatory and coagulation pathways.
- Results suggest that increased levels of urinary thrombin and MIF can serve as effective biomarkers for assessing inflammatory and hypercoagulable states in children suffering from IgAV.
[Urinary protein and renal pathological features in children with immunoglobulin A vasculitis with nephritis and hypercoagulability].
Zhongguo Dang Dai Er Ke Za Zhi
February 2024
Objectives: To study the association of hypercoagulability with urinary protein and renal pathological damage in children with immunoglobulin A vasculitis with nephritis (IgAVN).
Methods: Based on the results of coagulation function, 349 children with IgAVN were divided into a hypercoagulability group consisting of 52 children and a non-hypercoagulability group consisting of 297 children. Urinary protein and renal pathological features were compared between the two groups, and the factors influencing the formation of hypercoagulability in children with IgAVN were analyzed.
Objective: To explore the advantages of urinary matrix metalloproteinase-7 (MMP-7) in evaluating renal tubular injury in minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) patients compared with urinary cystatin C (CysC) and retinol-binding protein (RBP).
Methods: Serum and urine samples were collected from 20 healthy volunteers, and 40 MCD and 20 FSGS patients. Serum and urinary MMP-7 levels were measured by enzyme-linked immunosorbent assay.
Background: The CD47-SIRPα pathway acts as an important myeloid cell immune checkpoint and targeting the CD47/SIRPα axis represents a promising strategy to promote antitumor immunity. Several CD47-targeting agents show encouraging early activity in clinical trials. However, due to ubiquitous expression of CD47, the antigen sink and hematologic toxicity, such as anemia and thrombocytopenia, are main problems for developing CD47-targeting therapies.
View Article and Find Full Text PDF[An introduction of different positioning tests of benign paroxysmal positional vertigo and their clinical values].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
October 2010
Objective: To explore the clinical value of different positioning tests for different benign paroxysmal positional vertigo (BPPV).
Method: This research applies Dix-Hallpike test and Side-lying test for PC-BPPV, Roll test and WRW test for HC-BPPV, Dix-Hallpike test, Side-lying test and Rahko T maneuvers for SC-BPPV. Six hundred and thirteen cases, who were tested with different positioning tests in the sequence of firstly PC-BPPV then HC-BPPV and finally SC-BPPV, were randomly divided into 2 groups.