Planar chiral metasurfaces with maximal and tunable chiroptical response driven by bound states in the continuum.

Optical metasurfaces with high quality factors (Q-factors) of chiral resonances can boost substantially light-matter interaction for various applications of chiral response in ultrathin, active, and nonlinear metadevices. However, current approaches lack the flexibility to enhance and tune the chirality and Q-factor simultaneously. Here, we suggest a design of chiral metasurface supporting bound state in the continuum (BIC) and demonstrate experimentally chiroptical responses with ultra-high Q-factors and near-perfect circular dichroism (CD = 0.

Laser nanoprinting of floating three-dimensional plasmonic color in pH-responsive hydrogel.

Recent demonstrations of metasurfaces present their great potential to implement flat and multifunctional optical elements, which are accomplished with the designs of planar optics and micro-/nano- fabrications. Integrating metasurfaces in three dimensions has manifested drastically increasing advantages in manipulating light fields by extending design freedom. However, fabricating three-dimensional metasurfaces remain a tough challenge due to the lack of stereo printing protocols.

3D high precision laser printing of a flat nanofocalizer for subwavelength light spot array.

Here, we demonstrate a flat nanofocalizer for converging light field into a uniform subwavelength light spot array based on the fractional Talbot effect by developing a direct laser writing technique with 3D fabrication precision. The fractional Talbot effect endows the device with the merits of high compression ratio and modular design capability for transforming a plane wave into arrayed light focal spots. By combining a synergistic laser printing technique, we introduce a buffer layer for improving the fabrication precision of structural height in favor of accurately manipulating the phase delay.

Dopaminergic axons preferentially innervate dendritic spines with hyperactive glutamatergic synapses in the rat striatum.

Dopaminergic and glutamatergic afferents simultaneously innervate median spiny neurons (MSNs) and interact to mediate basal ganglia functions. However, the association between dopaminergic and glutamatergic axons is not clear. In the present study, nigrostriatal, corticostriatal, and thalamostriatal axons were anterogradely traced with biotinylated dextran amines (BDA) in rats, and MSNs were labeled with chloromethylbenzamido-DiI for neurogeometric analysis.

Long-term changes in morphology, D2R expression and targets of regenerated dopaminergic terminals in the striatum after a partial lesion in the substantia nigra in the rat.

During Parkinson's disease (PD), compensatory regeneration or sprouting of fibers from surviving dopaminergic neurons in the striatum occurs in response to the lesion in the substantia nigra pars compacta (SNpc). The morphological characteristics of regenerated terminal have previously been shown to differ from normal terminals. Here, we provide insights into the morphological characteristics of regenerated dopaminergic terminals in the striatum over a 16-week period after a partial SNpc lesion.

Antihypoxic effects of neuroglobin in hypoxia-preconditioned mice and SH-SY5Y cells.

This work aims at investigating the neuroprotective effects of neuroglobin (Ngb) in vivo and in vitro. RT-PCR and Western blotting were used to examine Ngb mRNA and protein levels in the mouse cortex after acute and repeated exposure to hypoxia. The cDNAs of mouse Ngb were cloned and transfected into SH-SY5Y cells to examine Ngb function in vitro.