sp. nov., isolated from deep-sea sediment of the Pacific Ocean.

A taxonomic study was carried out on strain PA15-N-34, which was isolated from deep-sea sediment of Pacific Ocean. The bacterium was Gram-stain-positive, oxidase- and catalase-positive and rod-shaped. Growth was observed at salinity of 0-15.

Chengkuizengella marina sp. nov., isolated from deep-sea sediment of the Pacific Ocean.

A taxonomic study was carried out on strain YPA3-1-1, which was isolated from deep-sea sediment of the Pacific Ocean. The bacterium was Gram-stain-positive, oxidase-positive, catalase-negative, rod-shaped and spore-forming. Growth was observed at salinities of 1.

14-3-3 proteins interact with neurofilament protein-L and regulate dynamic assembly of neurofilaments.

Neurofilament protein-L (NF-L) is the core component of neurofilaments. Recent studies indicate that the NF-L mutations reported in human Charcot-Marie-Tooth (CMT) disease lead to the formation of NF-L aggregates and result in axon degeneration of motor and sensory neurons, which are thought to be the cause of CMT disease type 2E. In the present study, we investigated the dynamic regulation of NF-L assembly and the mechanism of aggregate formation of CMT NF-L mutants.