Intraoperative bulbocavernosus reflex monitoring for predicting postoperative voiding dysfunction in patients with distal intraspinal tumors.

Objective: To investigate the predictive value of intraoperative bulbocavernosus reflex (BCR) monitoring for voiding dysfunction post-operatively in patients with distal intraspinal tumors and to determine an appropriate timing for postoperative follow-up assessment.

Methods: Patients with distal intraspinal tumors who underwent surgery with BCR monitoring were collected. Patients were classified into BCR absent and present groups according to the monitoring responses at the end of surgery.

MR-guided laser interstitial thermal therapy for drug-resistant lesional epilepsy: a single-center experience.

Background: To describe and report the efficacy and safety of MR-guided laser interstitial thermal therapy (MRgLITT) in the treatment of drug-resistant epilepsy.

Methods: A retrospective review of all MRgLITT procedures in our hospital was performed. All procedures were performed using a surgical laser ablation system.

Neurosyphilis with positive anti-N-methyl-D-aspartate receptor antibody: a case report.

A case of neurosyphilis with a positive anti-N-methyl-D-aspartate receptor (NMDAR) antibody was reported. A 54-year-old man who presented with acute memory deficits was admitted to our hospital. Acute ischemic stroke (AIS) was initially considered, and he was prescribed intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA).

Epileptic Tissue Localization through Skewness-Based Functional Connectivity in the High-Frequency Band of Intracranial EEG.

Functional connectivity analysis of intracranial electroencephalography (iEEG) plays an important role in understanding the mechanism of epilepsy and seizure dynamics. However, existing connectivity analysis is only suitable for low-frequency bands below 80 Hz. High-frequency oscillations (HFOs) and high-frequency activity (HFA) in the high-frequency band (80-500 Hz) are thought to be specific biomarkers in epileptic tissue localization.

Automatic Epileptic Tissue Localization through Spatial Pattern Clustering of High Frequency Activity.

High-frequency activity (HFA) in intracranial electroencephalography recordings are diagnostic biomarkers for refractory epilepsy. Clinical utilities based on HFA have been extensively examined. HFA often exhibits different spatial patterns corresponding to specific states of neural activation, which will potentially improve epileptic tissue localization.

Prognostic values of optic nerve sheath diameter for comatose patients with acute stroke: An observational study.

Background: Optic nerve sheath diameter (ONSD) measurement is one of the non-invasive methods recommended for increased intracranial pressure (ICP) monitoring.

Aim: This study aimed to evaluate the roles of optic nerve sheath diameter (ONSD) and ONSD/eyeball transverse diameter (ETD) ratio in predicting prognosis of death in comatose patients with acute stroke during their hospitalization.

Methods: A total of 67 comatose patients with acute stroke were retrospectively recruited.

Neuronal intranuclear inclusion disease presented with recurrent vestibular migraine-like attack: a case presentation.

Background: Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder characterized by dementia, tremor, episodic encephalopathy and autonomic nervous dysfunction. To date, vestibular migraine (VM)-like attack has never been reported in cases with NIID. Here, we describe an 86-year-old patient with NIID who presented with recurrent vertigo associated with headache for more than 30 years.

The clinical and prognostic values of optic nerve sheath diameter and optic nerve sheath diameter/eyeball transverse diameter ratio in comatose patients with supratentorial lesions.

Background: The optic nerve sheath diameter (ONSD) and ONSD/eyeball transverse diameter (ETD) ratio have been proven to be correlated with intracranial pressure. This study aimed to evaluate the prognostic roles of ONSD and the ONSD/ETD ratio in comatose patients with supratentorial lesions and to determine the relationship of these two indices with the prognosis of such patients.

Methods: A total of 54 comatose patients with supratentorial lesions and 50 healthy controls were retrospectively included in this study.

Postoperative incidence of seizure and cerebral infarction in pediatric patients with epileptic type moyamoya disease: a meta-analysis of single rate.

Background: Surgery is a conventional mature treatment for moyamoya disease (MMD). However, whether surgery is also an effective therapy for epileptic type MMD has seldom been investigated systematically. The study aims to summarize the pooled postoperative incidence of seizure and cerebral infarction in pediatric patients with epileptic type moyamoya disease.

Electroencephalographic features in pediatric patients with moyamoya disease in China.

Background: Moyamoya disease (MMD) is a relatively important and common disease, especially in East Asian children. There are few reports about EEG in children with MMD in China till now. This study is aimed to analyze the electroencephalographic features of MMD in pediatric patients in China preliminarily.

Hypothalamic sydrome as an initial presentation of Wernicke encephalopathy: A case report.

Rationale: Wernicke encephalopathy (WE) is a syndrome characterized by an acute or subacute onset of ataxia, ophthalmoplegia, and mental status changes. To our knowledge, hypothalamic syndrome is rare in WE.

Patient Concerns: A 73-year-old female patient with acute cerebral infarct, who showed initial symptoms of vomiting, nausea, ataxia, and subsequent anorexia, was treated with parenteral nutritional supplement for 20 days.

Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma-related epilepsy.

Background: Glioma-related epilepsy (GRE) is defined as symptomatic epileptic seizures secondary to gliomas, it brings both heavy financial and psychosocial burdens to patients with diffuse glioma and significantly decreases their quality of life. To date, there have been no clinical guidelines that provide recommendations for the optimal diagnostic and therapeutic procedures for GRE patients.

Methods: In March 2017, the Joint Task Force for GRE of China Association Against Epilepsy and Society for Neuro-Oncology of China launched the guideline committee for the diagnosis and treatment of GRE.

Current status and potential application of navigated transcranial magnetic stimulation in neurosurgery: a literature review.

Transcranial magnetic stimulation (TMS) is a noninvasive neurophysiologic technique that can stimulate the human brain. Positioning of the coil was often performed based merely on external landmarks on the head, meaning that the anatomical target in the cortex remains inaccurate. Navigated transcranial magnetic stimulation (nTMS) combines a frameless stereotactic navigational system and TMS coil and can provide a highly accurate delivery of TMS pulses with the guidance of imaging.

Topography of Synchronization of Somatosensory Evoked Potentials Elicited by Stimulation of the Sciatic Nerve in Rat.

Purpose: Traditionally, the topography of somatosensory evoked potentials (SEPs) is generated based on amplitude and latency. However, this operation focuses on the physical morphology and field potential-power, so it suffers from difficulties in performing identification in an objective manner. In this study, measurement of the synchronization of SEPs is proposed as a method to explore brain functional networks as well as the plasticity after peripheral nerve injury.

[Application of continuous video-electroencephalographic monitoring in patients with consciousness disorders in intensive care unit].

Objective: To evaluate the application value of continuous video-electroencephalographic (cVEEG) monitoring in patients with consciousness disorders in intensive care unit (ICU).

Methods: Retrospective analyses were conducted for applying cVEEG in the clinical diagnosis and outcome evaluation of 54 patients with consciousness disorders in intensive care unit (ICU) at our hospital from January 2008 to April 2014.

Results: The most common cause was cerebrovascular disease (46.

An EEMD-ICA Approach to Enhancing Artifact Rejection for Noisy Multivariate Neural Data.

As neural data are generally noisy, artifact rejection is crucial for data preprocessing. It has long been a grand research challenge for an approach which is able: 1) to remove the artifacts and 2) to avoid loss or disruption of the structural information at the same time, thus the risk of introducing bias to data interpretation may be minimized. In this study, an approach (namely EEMD-ICA) was proposed to first decompose multivariate neural data that are possibly noisy into intrinsic mode functions (IMFs) using ensemble empirical mode decomposition (EEMD).

Using Relevance Feedback to Distinguish the Changes in EEG During Different Absence Seizure Phases.

We carried out a series of statistical experiments to explore the utility of using relevance feedback on electroencephalogram (EEG) data to distinguish between different activity states in human absence epilepsy. EEG recordings from 10 patients with absence epilepsy are sampled, filtered, selected, and dissected from seizure-free, preseizure, and seizure phases. A total of 112 two-second 19-channel EEG epochs from 10 patients were selected from each phase.

[Paroxysmal kinesigenic dyskinesia: 2 case reports].

Paroxysmal kinesigenic dyskinesia (PKD) is a rare neurological condition in which brief and frequent dyskinetic attacks are provoked by sudden movement. PKD is more common in men and can be idiopathic (commonly familial) or due to a variety of causes. The pathophysiology of PKD is uncertain but it could be an ion-channel disorder.

Classifying normal and abnormal status based on video recordings of epileptic patients.

Based on video recordings of the movement of the patients with epilepsy, this paper proposed a human action recognition scheme to detect distinct motion patterns and to distinguish the normal status from the abnormal status of epileptic patients. The scheme first extracts local features and holistic features, which are complementary to each other. Afterwards, a support vector machine is applied to classification.

Dynamic characteristics of absence EEG recordings with multiscale permutation entropy analysis.

Understanding the transition of brain activities towards an absence seizure, called pre-epileptic seizure, is a challenge. In this study, multiscale permutation entropy (MPE) is proposed to describe dynamical characteristics of electroencephalograph (EEG) recordings on different absence seizure states. The classification ability of the MPE measures using linear discriminant analysis is evaluated by a series of experiments.

Estimation of genuine and random synchronization in multivariate neural series.

Synchronization is an important mechanism that helps in understanding information processing in a normal or abnormal brain. In this paper, we propose a new method to estimate the genuine and random synchronization indexes in multivariate neural series, denoted as GSI (genuine synchronization index) and RSI (random synchronization index), by means of a correlation matrix analysis and surrogate technique. The performance of the method is evaluated by using a multi-channel neural mass model (MNMM), including the effects of different coupling coefficients, signal to noise ratios (SNRs) and time-window widths on the estimation of the GSI and RSI.

TDAG51 in the anterior temporal neocortex of patients with intractable epilepsy.

TDAG51 (T cell death-associated gene 51) is an apoptosis-associated protein. Our aim was to investigate TDAG51 expression in the anterior temporal neocortex of patients with intractable epilepsy (IE), and then to discuss the possible role of TDAG51 in IE. Tissue samples from the anterior temporal neocortex of 33 patients who had surgery for IE were used to detect TDAG51 expression by immunohistochemistry, immunofluorescence, and Western blotting.

Impaired single cell firing and long-term potentiation parallels memory impairment following recurrent seizures.

Patients with epilepsy are at substantial risk for memory impairment. Animal studies have paralleled these clinical observations, demonstrating impaired hippocampal function as measured by spatial memory in rodents subjected to seizures. However, the mechanism of seizure-induced hippocampal impairment is unclear.