Synopsis of recent research by authors named "Xianyu Bian"
- Xianyu Bian's recent research focuses on developing innovative vaccine strategies against porcine rotaviruses (PoRVs), which are significant pathogens causing diarrhea in piglets and contributing to considerable economic losses in the swine industry
- The studies have explored the efficacy of recombinant proteins, demonstrating that a combination of nonstructural protein 4 (NSP4) and structural protein VP4 can elicit strong mucosal responses, and that a bivalent subunit vaccine using truncated VP4 proteins from key circulating genotypes can induce protective immunity
- Additionally, Bian's research includes the isolation and characterization of a new porcine rotavirus strain (G9P[23]), highlighting the genetic diversity of rotaviruses in Chinese pig populations and underscoring the need for tailored vaccine approaches to address varying strains
