Differences analysis between spinal tuberculosis and brucella spondylitis with preoperative non-invasive differential diagnosis.

Objective: Spinal tuberculosis (STB) and Brucella spondylitis (BS) represent two types of granulomatous infections affecting the spine, which exhibit significant similarities that often result in misdiagnosis and overlooked diagnoses during preoperative evaluations. This study aims to identify non-invasive evaluative indicators that facilitate the differentiation between STB and BS.

Methods: This study conducted a retrospective collection of clinical features, laboratory tests, and imaging characteristics from 89 patients diagnosed with STB and 66 patients diagnosed with BS.

Research Progress on the Role of Cartilage Endplate in Intervertebral Disc Degeneration.

Low back pain significantly impacts individuals' quality of life, with intervertebral disc degeneration (IDD) being a primary contributor to this condition. Currently, IDD treatment primarily focuses on symptom management and does not achieve a definitive cure. The cartilage endplate (CEP), a crucial nutrient-supplying tissue of the intervertebral disc, plays a pivotal role in disc degeneration.

Effectiveness and Safety of High-Dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Surgery: A Meta-Analysis and Systematic Review.

Objective: This systematic review and meta-analysis of randomized controlled trials and retrospective controlled studies aims to evaluate the efficacy and safety of high-dose tranexamic acid (TXA) in spinal correction surgery for adolescent idiopathic scoliosis patients.

Methods: In March 2024, a comprehensive search was conducted in PubMed, Web of Science, Embase, and Cochrane databases to identify randomized controlled trials and retrospective controlled studies comparing the effects of high-dose TXA on blood loss and transfusion requirements during spinal correction surgery.

Results: This meta-analysis included 10 studies encompassing a total of 741 patients.

Research Progress of Long Non-coding RNA-ZFAS1 in Malignant Tumors.

Long non-coding RNAs (lncRNAs), although incapable of encoding proteins, play crucial roles in multiple layers of gene expression regulation, epigenetic modifications, and post-transcriptional regulation. Zinc finger antisense 1 (ZFAS1), a lncRNA located in the 20q13 region of the human genome, exhibits dual functions as an oncogene or tumor suppressor in various human malignancies. ZFAS1 plays a crucial role in cancer progression, metastasis, invasion, apoptosis, cell cycle regulation, and drug resistance through complex molecular mechanisms.

Research progress on long non‑coding RNAs in non‑infectious spinal diseases (Review).

Spinal diseases, including intervertebral disc degeneration (IDD), ankylosing spondylitis, spinal cord injury and other non‑infectious spinal diseases, severely affect the quality of life of patients. Current treatments for IDD and other spinal diseases can only relieve symptoms and do not completely cure the disease. Therefore, there is an urgent need to explore the causes of these diseases and develop new treatment approaches.

[Aerobic denitrification of nitrate wastewater and changes of microbial community structure in a bio-ceramic reactor].

Biological treatment of nitrate wastewater with aerobic denitrifiers in a bio-ceramic reactor was investigated. And denaturing gradient gel electrophoresis (DGGE) method was used for analyzing the stability of microbial community structure. At the condition of the influent with hydraulic loading 0.

[Identification and characterization of a bacterial strain C3 capable of aerobic denitrification].

A bacterial strain C3 screened from the activated sludge was found capable of aerobic denitrification and the denitrifying capability of the strain was studied in batch culture under aerobic condition. The results showed that the nitrate in the culture could be efficiently removed by strain C3 and the nitrogen removal rate was up to above 90%. According to the morphological observation, physiological biochemical test and sequence analysis of the 16S rDNA, strain C3 was identified as Pseudomonas sp.