Lead-Free Bismuth-Based Perovskite X-ray Detector with High Sensitivity and Low Detection Limit.

Bismuth-based halide perovskites have shown great potential for direct X-ray detection, attributable to their nontoxicity and advantages in detection sensitivity and spatial resolution. However, the practical application of such materials still faces the critical challenge of combining both high sensitivity and low detection limits. Here, we report a new type of zero-dimensional (0D) perovskite (HIS)BiI (, where HIS = histamine) with high sensitivity and a low detection limit.

Tailoring a Two-Dimensional Halide Perovskite Composed of the Secondary Amine Cation for Anisotropic X-ray Responses.

Two-dimensional (2D) metal-halide perovskites have shown broad application prospects in the field of optoelectronic detection. The presence of the natural quantum-well structure results in strong anisotropy of physical properties, while studies on anisotropic X-ray responses remain insufficient. Here, we present an intriguing anisotropy of X-ray-responsive behaviors in a 2D halide perovskite, (-ACH)(DMA)PbBr (, where -ACH is -4-(aminomethyl)cyclohexanecarboxylate and DMA is dimethylamine), in which the secondary amine DMA cation with a large ionic radius locates inside the perovskite cage to form inorganic frameworks.

Evaluating linezolid dose regimens against methicillin-resistant Staphylococcus aureus based on renal function in populations with different body weight.

What Is Known And Objective: Linezolid is an alternative first-line agent for MRSA pneumonia. This study assessed whether dose adjustments of linezolid against methicillin-resistant Staphylococcus aureus (MRSA) infections were needed based on renal function in populations with different body weight.

Methods: Monte Carlo simulations were conducted to evaluate renal function in relation to the probability of target attainment (PTA) in three population groups with different body weight.

Prescreening for osteoporosis with forearm bone densitometry in health examination population.

Background: Early detection and timely prophylaxis can retard the progression of osteoporosis. The purpose of this study was to determine the validity of peripheral Dual Energy X-ray Absorptiometry (DXA) test for osteoporosis screening. We examined peripheral bone mineral density (BMD) using AKDX-09 W-I DXA densitometer.

Drug-drug interaction comparison between tacrolimus and phenobarbital in different formulations for paediatrics and adults.

To compare drug-drug interaction (DDI) between tacrolimus and different formulations of phenobarbital in paediatrics and adults.Physiologically based pharmacokinetics (PBPK) models were used to evaluate DDI between phenobarbital (oral (p.o.

Lead chlorine cluster assembled one-dimensional halide with highly efficient broadband white-light emission.

One new type of hybrid lead halide of [DTHPE]2Pb3Cl10 has been synthesized and characterized containing a one-dimensional (1D) wavelike [Pb3Cl10]4- chain based on a corner-shared [Pb3Cl11] cluster. Remarkably, this cluster-based 1D chain displays intrinsic broadband white light emission with a high quantum efficiency of 19.45% exceeding those of previously reported typical two-dimensional perovskites.

Psychological Behavior of Frontline Medical Staff in the Use of Preventive Medication for COVID-19: A Cross-Sectional Study.

Purpose: To understand the current pandemic, levels of anxiety in frontline staff, and whether they have been using medication to prevent COVID-19.

Methods: Between January 10 and March 10, 2020, 290 frontline staff completed a questionnaire incorporating the Generalized Anxiety Disorder Scale 7 (GAD-7) to indicate their psychological behavior in the use of preventive medication.

Results: Of those who participated in the study, 77.

Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study.

Background: The purpose of the study is to describe the blood lipid levels of patients diagnosed with coronavirus disease 2019 (COVID-19) and to analyze the correlation between blood lipid levels and the prognosis of COVID-19 patients.

Methods: In the clinical retrospective analysis, a total of 228 adults infected with COVID-19 were enrolled between January 17, 2020 and March 14, 2020, in Changsha, China. One thousand one hundred and forty healthy participants with matched age and gender were used as control.

Factors Associated With Job Satisfaction of Frontline Medical Staff Fighting Against COVID-19: A Cross-Sectional Study in China.

The current research on frontline medical staff in China fighting against COVID-19 has not yet addressed job satisfaction. The purpose of this study is to investigate the job satisfaction of those who were sent to support Hubei province, China, or worked in local designated hospitals, and then analyze the associated influencing factors. A total of 455 medical staff who worked at the frontline of the prevention and control of COVID-19 in Hubei province was selected using simple random sampling.

A three-dimensional cuprous lead bromide framework with highly efficient and stable thermochromic luminescence properties.

Herein, by using a structural design strategy of incorporating hetrometallic halide blocks, we prepared the first 3D bimetallic halide of [HDABCO]CuPbBr with new topological network based on two types of 6-connected nodes. Remarkably, this 3D framework displays highly efficient thermochromic luminescence from broadband yellow to green light emissions with remarkable stability.

Intestinal absorption of raltitrexed and evaluation of the effects of absorption enhancers.

Raltitrexed (RTX) has shown clinical activity in a variety of advanced solid tumours. Its oral bioavailability is low and its intestinal absorption mechanism is not clear. In the present study, the absorption mechanism of RTX in the small intestine was investigated, and the effects of absorption enhancers and efflux transporter inhibitors were evaluated by in vitro transport studies using the Caco-2 cell model and in situ perfusion experiments in rats.