Synopsis of recent research by authors named "Xiankuo Yu"
- Xiankuo Yu's recent research primarily focuses on examining the therapeutic potential of traditional Chinese medicine (TCM) and its components against various cancer types, utilizing innovative high-throughput screening (HTS) technologies to discover and analyze compounds that inhibit cancer cell proliferation and modulate immune responses.
- Notable findings include the role of TRIB3 as a prognostic biomarker across multiple cancers, the identification of ginsenoside F2 as an inhibitor of hepatocellular carcinoma through STAT3 suppression, and the anticancer effects of traditional formulations like Yupingfeng San and Guizhi Fuling Decoction via MAPK and PI3K pathway modulation.
- The research underscores the significance of integrating molecular pharmacology with ethnopharmacological insights, highlighting the need for comprehensive studies on the pharmacokinetics and mechanisms of action of TCM compounds to advance their efficacy and safety in clinical applications.
