Publications by authors named "Xiankun Zhou"
Article Synopsis
- - Angiogenesis, crucial for processes like embryonic development and cancer, is influenced by long noncoding RNAs (lncRNAs), which regulate gene expression, including the lncRNA MYU that enhances prostate cancer and is upregulated in hypoxic conditions.
- - The study focused on MYU's role in promoting angiogenesis in vascular endothelial cells under hypoxia, examining its impact on the expression of miR-23a-3p and interleukin-8 (IL-8) in human umbilical vein endothelial cells (HUVECs).
- - Results showed that increased MYU levels and decreased miR-23a-3p led to enhanced proliferation, migration, and tube formation of H
Article Synopsis
- The study focuses on TMEM8c (Myomaker), a protein important for skeletal muscle development, particularly in pigs.
- Researchers found that miR-205 inhibits myoblast fusion by targeting Myomaker, complicating muscle growth and healing.
- When analyzing muscle injury in pigs, they observed that Myomaker expression increased while miR-205 decreased, suggesting a critical role for Myomaker in muscle regeneration.
miR-361-3p mitigates hypoxia-induced cardiomyocyte injury via targeting apoptosis initiators caspase-2/-8/-9.
In Vitro Cell Dev Biol Anim
February 2022
Acute myocardial infarction (AMI) is an ischemic heart disease with high mortality. AMI-induced hypoxia will trigger serious myocardial injury, such as cardiomyocyte apoptosis. miRNAs have been reported to be involved in the development of AMI.
View Article and Find Full Text PDFLocal hypoxia has recently been reported to occur in the white adipose tissue (WAT) microenvironment during obesity. Adipocytes have a unique life cycle that reflects the different stages of adipogenesis in the WAT niche. Long non-coding RNAs (lncRNAs) play an important role in the cellular response to hypoxia.
View Article and Find Full Text PDFThis study investigates the effect of aluminum (Al) on the microstructure, micro-hardness, and wettability of environmentally friendly Sn-20Bi-xAl (x = 0, 0.1, 0.3, 0.
View Article and Find Full Text PDFGuanidinoacetic acid (GAA), an amino acid derivative that is endogenous to animal tissues including muscle and nerve, has been reported to enhance muscular performance. MicroRNA (miRNA) is a post-transcriptional regulator that plays a key role in nutrient-mediated myogenesis. However, the effects of GAA on myogenic differentiation and skeletal muscle growth, and the potential regulatory mechanisms of miRNA in these processes have not been elucidated.
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