Publications by authors named "Xianjie Xiao"
Aim: To explore the safety and efficacy of a novel strategy (bi-atrial linear catheter ablation guided by electrophysiological mapping) for persistent atrial fibrillation (PeAF) treatment.
Methods: 83 patients with PeAF were enrolled for evaluation of ablation strategy. 43 patients were subjected to pulmonary vein isolation (PVI) strategy (PVI group).
(1) Background: A plethora of studies have elucidated the safety and efficacy of catheter ablation (CA) for patients afflicted with atrial fibrillation (AF) and concomitant reduction in left ventricular ejection fraction (LVEF). Nevertheless, the literature on the benefits of CA in the specific etiological context of heart failure (HF) remains limited. This study delineates a comparative assessment of outcomes for patients with AF and reduced LVEF across the primary etiologies.
View Article and Find Full Text PDFObjective: To identify the predictors of pacing-induced cardiomyopathy (PICM) and illustrate the safety and feasibility of conduction system pacing (CSP) upgrade on patients with long-term persistent atrial fibrillation (AF).
Methods: All patients with long-term persistent AF and normal left ventricular ejection fraction (LVEF) ≥50% were consecutively enrolled from January 2008 to December 2017, and all the patients with atrioventricular block (AVB) and high right ventricular pacing (RVP) percentage of at least 40%. The predictors of PICM were identified, and patients with PICM were followed up for at least 1 year regardless of CSP upgrade.
Background: The use of contact force (CF) sensing catheters has provided a revolutionary improvement in catheter ablation (CA) of atrial fibrillation (AF) in the past decade. However, the success rate of CA for AF remains limited, and some complications still occur.
Methods: The TRUEFORCE trial (Catheter Ablation of Atrial Fibrillation using FireMagic TrueForce Ablation Catheter) is a multicenter, prospective, single-arm objective performance criteria study of AF patients who underwent their first CA procedure using FireMagic TrueForce ablation catheter.
Objective: The purpose of this study was to evaluate the feasibility and outcomes of conduction system pacing (CSP) in patients with heart failure (HF) who had a severely reduced left ventricular ejection fraction (LVEF) of less than 30% (HFsrEF).
Methods: Between January 2018 and December 2020, all consecutive HF patients with LVEF < 30% who underwent CSP at our center were evaluated. Clinical outcomes and echocardiographic data [LVEF and left ventricular end-systolic volume (LVESV)], and complications were all recorded.
Rationale: We reported a case with cardiomyopathy induced by frequent premature ventricular contractions (PVCs) and followed ventricular escape beats (VEBs). PVCs with VEBs in the compensatory pause which induced cardiomyopathy is rarely reported. Also, the case exhibited many characteristics of PVCs which were more likely to induce cardiomyopathy, like the location of origin, the longer coupling interval, and the QRS wave companied with the P wave.
View Article and Find Full Text PDFThe optimal catheter ablation (CA) strategy for patients with persistent atrial fibrillation (PeAF) and heart failure (HF) remains uncertain. Between 2016 and 2020, 118 consecutive patients with PeAF and HF who underwent the CA procedure in two centers were retrospectively evaluated and divided into the pulmonary vein isolation (PVI)-only and PVI + additional ablation groups. Transthoracic echocardiography (TTE) was performed at baseline, one month, and 12 months after the CA procedure.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated how baseline impedance impacts the effectiveness of radiofrequency ablation in patients with paroxysmal atrial fibrillation (PAF), using the ablation index (AI) as a guide.
- Conducted as a retrospective analysis of 101 patients, the results showed that lower baseline impedance was associated with better outcomes, with an 82.2% success rate in preventing AF recurrence over an average follow-up of 12 months.
- Findings suggest that baseline impedance, along with other factors like PAF duration and AI levels, is a key predictor of recurrence, indicating that higher impedance may lead to less effective ablation lesions.
Catheter ablation should be considered in patients with atrial fibrillation (AF) and with heart failure (HF) with reduced ejection fraction (EF; HFrEF) to improve survival and reduce heart failure hospitalization. Careful patient selection for AF ablation is key to achieving similar outcome benefits. However, limited data exist regarding predictors of recovered ejection fraction.
View Article and Find Full Text PDFArticle Synopsis
- Catheter ablation is a viable alternative to pacemaker implantation for patients with tachycardia-bradycardia syndrome, resulting in better outcomes regarding heart-related complications and hospitalization.
- A study involving 306 TBS patients found that those who underwent catheter ablation experienced significantly lower rates of death, cardiovascular-related hospitalizations, and thrombosis events compared to those who received pacemakers.
- In addition, patients treated with ablation had a lower progression to persistent atrial fibrillation and required fewer antiarrhythmic and anticoagulant medications.
Appropriate intraprocedural initial heparin dosing in patients undergoing catheter ablation for atrial fibrillation receiving uninterrupted non-vitamin-K antagonist oral anticoagulant treatment.
BMC Cardiovasc Disord
April 2021
Background: To clarify the appropriate initial dosage of heparin during radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF) receiving uninterrupted nonvitamin K antagonist oral anticoagulant (NOAC) treatment.
Methods: A total of 187 consecutive AF patients who underwent their first RFCA in our center were included. In the warfarin group (WG), an initial heparin dose of 100 U/kg was administered (control group: n = 38).
Article Synopsis
- The study explores the feasibility and safety of high-power, short-duration (HPSD) radiofrequency ablation for treating arrhythmias in the coronary sinus, a challenging area for ablation procedures.
- Four clinical cases showed successful results with HPSD after initial failures using standard methods, and in vitro experiments on swine hearts compared HPSD to traditional low-power, long-duration techniques.
- Results indicated that HPSD created larger and more effective lesions than the conventional approach, although further studies are needed to ensure its safety.
Article Synopsis
- * Eighteen patients underwent procedures utilizing a 3D mapping system (CARTO3) for precise location during AVN ablation and lead implantation, with successful outcomes in 17 cases.
- * The procedure had an average duration of about 99 minutes and demonstrated high efficiency, indicating that real-time 3D mapping is a valuable tool in these cardiac interventions.
We evaluated whether an irrigated contact force-sensing catheter would improve the safety and effectiveness of radiofrequency ablation of premature ventricular contractions originating from the right ventricular outflow tract. We retrospectively reviewed the charts of patients with symptomatic premature ventricular contractions who underwent ablation with a contact force-sensing catheter (56 patients, SmartTouch) or conventional catheter (59 patients, ThermoCool) at our hospital from August 2013 through December 2015. During a mean follow-up of 16 ± 5 months, 3 patients in the conventional group had recurrences, compared with none in the contact force group.
View Article and Find Full Text PDFArticle Synopsis
- A study compared the effectiveness of cryoballoon ablation for atrial fibrillation (AF) with and without transesophageal echocardiography (TEE) guidance in 80 patients.
- The TEE group had significantly less fluoroscopy time and required less contrast agent compared to the non-TEE group, while both groups had similar procedure times and success rates after follow-up.
- The findings suggest that using TEE during cryoballoon ablation is safe, effective, and reduces exposure to fluoroscopy and contrast agents.
Background: Atrial fibrillation (AF) is an established risk factor of left atrial thrombosis and systemic embolism. Traditionally pulmonary embolism (PE) is a recognized complication of deep vein thrombosis (DVT). However, whether AF is responsible for right atrial thrombosis and leads to PE has not been examined.
View Article and Find Full Text PDFBackground: The association between dyslipidemia, a major risk factor for cardiovascular diseases, and atrial fibrillation (AF) is not clear because of limited evidence.
Hypothesis: Dyslipidemia may be associated with increased risk of AF in a Chinese population.
Methods: A total of 88 785 participants free from AF at baseline (2006-2007) were identified from the Kailuan Study.
Background: The coronary sinus (CS), as a junction of the atria, contributes to atrial fibrillation (AF) by developing unstable reentry, and isolating the atria by ablation at the CS could terminate AF. The present study evaluated whether AF activities at the CS in a subset of patients contributed to AF maintenance and predicted clinical outcome of ablation.
Methods And Results: We studied 122 consecutive patients who had a first-time radiofrequency ablation for persistent AF.
Background: Atrial electrical remodeling (AER) is the underlying mechanism of atrial fibrillation (AF). The present study investigated the impact of epicardial fat pad (FP) ablation on acute AER (AAER) and inducibility of AF.
Methods And Results: AAER was performed in 28 mongrel dogs through 4-h rapid atrial pacing (RAP).