Publications by authors named "Xiangyue Zhu"
Crystal structure of F10 core protein from Mpox virus reveals its potential inhibitors.
Int J Biol Macromol
January 2025
Article Synopsis
- Mpox virus (MPXV) is a rare zoonotic disease that has resulted in over 15,600 cases and 537 deaths to date.
- The study focuses on the RNA polymerase (RNAP) of MPXV, which is crucial for early transcription, and reveals the high-resolution crystal structure of the F10 core protein, which stabilizes essential components of the RNAP complex.
- The research identified a cavity in the RNAP structure and screened 28 potential inhibitors, marking a significant step towards developing treatments for MPXV and similar emerging pathogens.*
To explore the adoption effect of nano-silver medical antibacterial dressing in the perioperative treatment of patients with laryngeal cancer, 120 patients with early laryngeal cancer were selected as the research objects. According to the different treatments, they were averagely divided into the test group (laser vocal cord surgery under a laryngeal microscope and nano-silver medical antibacterial dressing) and the control group (laser vocal cord surgery under a laryngeal microscope and sterilized vaseline gauze). The results showed that there were considerable differences in dressing-change times, dressing-change cost, hospital stay, and recovery time between both groups (P<0.
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