Publications by authors named "Xiangyou Meng"

The present work describes the development of silk fibroin (SF)/chitosan (CS)-based porous composite anal fistula scaffold (SCAFS) with anti-inflammatory and healing functions. The SCAFS comprises an inner layer made from degummed silk fiber using a vertical braiding machine, and an outer layer created by freeze-drying a mixture of short SF fibers and curcumin (CUR)/5-aminosalicylic acid (5-ASA) loaded SF/CS solution. Results revealed that the SCAFS has high porosity of 42.

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Article Synopsis
  • Researchers discovered genomic safe harbor sites (SHSs) in human cells, which are crucial for stable transgene integration in therapies like regenerative medicine and immunotherapy.
  • Using the CRISPR-MAD7 system, they successfully integrated transgenes into various cell types, maintaining stable expression and validating the differentiation of engineered iPSCs into key immune cell lineages.
  • The study showed that NK cells derived from engineered iPSCs continued to express an anti-CD19 CAR, indicating that these SHSs can effectively be utilized for developing adoptive immunotherapies.
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Flexible pressure sensors have attracted tremendous attention from researchers for their widely applications in tactile artificial intelligence, electric skin, disease diagnosis, and healthcare monitoring. Obtaining flexible pressure sensors with high sensitivity in a low cost and convenient way remains a huge challenge. In this paper, the composite dielectric layer based on the mixture of carbon nanotubes (CNTs) with different aspect ratios and polydimethylsiloxane (PDMS) was employed in flexible capacitive pressure sensor to increase its sensitivity.

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