Publications by authors named "Xiangying Xi"
Article Synopsis
- * This study investigated the role of polo-like kinase-3 (PLK-3) in DR using experiments on rats and retinal cells exposed to high glucose levels, finding that PLK-3 levels were significantly lower in DR conditions.
- * Enhancing PLK-3 expression appeared to improve retinal health by promoting cell functions and influencing specific proteins like BAP1, suggesting that targeting PLK-3 could be a potential treatment avenue for DR.
Diabetic retinopathy (DR), a microvascular complication characterized by abnormal angiogenesis, is the most common reason for irreversible blindness. Glycoprotein non-metastatic melanoma protein B (GPNMB), as a transmembrane protein, was found to be associated with angiogenesis. This study aims to investigate the role of GPNMB in DR.
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