Impact of visual impairments on cognitive functions in older adults: insights from NHANES data.

Background: Visual impairments (VI) are common in the older adults and may affect cognitive functions through mechanisms such as reduced sensory input and increased social isolation. Although current understanding of this association is incomplete, evidence suggests a potential link between poor vision and cognitive decline. This study aims to investigate the relationship between Subjective Visual Impairment (SVI), Objective Visual Impairment (OVI), and cognitive decline in the older adults, and assess whether these associations remain significant after controlling for multiple confounding factors.

Analysis of the evolutionary process of traditional village spatial pattern: The case of Gaoyi village in Western Hunan, China.

The examination of the characteristic law of traditional village transformation over time represents a vital nexus in cultural heritage preservation and the transmission of vernacular culture. Historical event points were used to augment village development information, facilitating the restoration of the village's historical pattern. Geographical analysis methods, including Standard Deviation Ellipse Analysis (SDSEA), Nearest Neighbor Analysis (NNA), and Source-Destination Analysis (SDA), were employed to explore the characteristics of the village's geographical center of gravity, changes in concentration and dispersion, and functional transfer.

Customizing Pore Structure and Lithiophilic Sites Dual-Gradient Free-Standing 3D Lithium-Based Anode to Enable Excellent Lithium Metal Batteries.

Developing 3D hosts is one of the most promising strategies for putting forward the practical application of lithium(Li)-based anodes. However, the concentration polarization and uniform electric field of the traditional 3D hosts result in undesirable "top growth" of Li, reduced space utilization, and obnoxious dendrites. Herein, a novel dual-gradient 3D host (GDPL-3DH) simultaneously possessing gradient-distributed pore structure and lithiophilic sites is constructed by an electrospinning route.

Optimizing tradeoff strategies of soil microbial community between metabolic efficiency and resource acquisition along a natural regeneration chronosequence.

The tradeoff between community-level soil microbial metabolic efficiency and resource acquisition strategies during natural regeneration remains unclear. Herein, we examined variations in soil extracellular enzyme activity, microbial metabolic quotient (qCO), and microbial carbon use efficiency (CUE) along a chronosequence of natural regeneration by sampling secondary forests at 1, 10, 20, 30, 40, and 100 years after rubber plantation (RP) clearance. The results showed that the natural logarithms of carbon (C)-, nitrogen (N)-, and phosphorus (P)-acquiring enzyme activities were 1:1.

Insight into farming native microbiome by bioinoculant in soil-plant system.

Applying beneficial microorganisms (BM) as bioinoculants presents a promising soil-amendment strategy while impacting the native microbiome, which jointly alters soil-plant performance. Leveraging the untapped potential of native microbiomes alongside bioinoculants may enable farmers to sustainably regulate soil-plant systems via natural bioresources. This review synthesizes literature on native microbiome responses to BMs and their interactive effects on soil and plant performance.

Two new seco-abietane type diterpenoids from the leaves of .

Two new seco-abietane type diterpenoids, named as isodonserra acid A and B (), along with six known compounds, angustanoic acid A (), epipalustric acid (), raserrane (), 7-methoxy coumarin (), umbelliferone (), and (-)-loliolide (), were obtained from the leaves of . The new structures of compounds and were elucidated by analysing their 1D NMR, 2D NMR and HR-ESI-MS spectra. Compounds showed moderate hepatoprotective activity against APAP-induced HepG2 cell injury with a cell survival rate from 50.

Genome assembly of two diploid and one auto-tetraploid Cyclocarya paliurus genomes.

Cyclocarya paliurus, an endemic species in the genus Juglandaceae with the character of heterodichogamy, is one of triterpene-rich medicinal plants in China. To uncover the genetic mechanisms behind the special characteristics, we sequenced the genomes of two diploid (protandry, PA-dip and protogyny, PG-dip) and one auto-tetraploid (PA-tetra) C. paliurus genomes.

Genome-wide identification and comparative analysis of DNA methyltransferase and demethylase gene families in two ploidy Cyclocarya paliurus and their potential function in heterodichogamy.

Background: DNA methylation is one of the most abundant epigenetic modifications, which plays important roles in flower development, sex differentiation, and regulation of flowering time. Its pattern is affected by cytosine-5 DNA methyltransferase (C5-MTase) and DNA demethylase (dMTase). At present, there are no reports on C5-MTase and dMTase genes in heterodichogamous Cyclocarya paliurus.

Squalene epoxidase (SE) gene related to triterpenoid biosynthesis assists to select elite genotypes in medicinal plant: Cyclocarya paliurus (Batal.) Iljinskaja.

Triterpenoids, known for their anti-inflammatory, anticancer, and hypoglycemic properties, are the major bioactive components in Cyclocarya paliurus (Batal.) Iljinskaja. Selecting elite individuals with high triterpenoids content is the basis of C.

Whole-genome Duplication Reshaped Adaptive Evolution in A Relict Plant Species, Cyclocarya paliurus.

Cyclocarya paliurus is a relict plant species that survived the last glacial period and shows a population expansion recently. Its leaves have been traditionally used to treat obesity and diabetes with the well-known active ingredient cyclocaric acid B. Here, we presented three C.

Construction of the dynamic model of SCI rehabilitation using bidirectional stimulation and its application in rehabilitating with BCI.

Unlabelled: Patients with complete spinal cord injury have a complete loss of motor and sensory functions below the injury plane, leading to a complete loss of function of the nerve pathway in the injured area. Improving the microenvironment in the injured area of patients with spinal cord injury, promoting axon regeneration of the nerve cells is challenging research fields. The brain-computer interface rehabilitation system is different from the other rehabilitation techniques.

Hexachloro-1,3-butadiene as a Functional Additive for Constructing an Efficient Solid Electrolyte Interface Layer for Long-Life Stable Li Anodes.

Lithium (Li) metal is considered as one of the attractive anodes for next-generation high-energy-density batteries due to its ultrahigh theoretical specific capacity and low potential. However, many great challenges including uncontrolled dendrite growth and undesired side reactions during repeated cycling still seriously hinder its practical application in Li metal secondary batteries. Herein, we report the hexachloro-1,3-butadiene (HCBD) molecule as a functional additive to stabilize the Li anode by forming a stable solid electrolyte interface (SEI) layer with high Li ion conductivity via in situ surface and electrochemical reactions.

BCI system with lower-limb robot improves rehabilitation in spinal cord injury patients through short-term training: a pilot study.

Unlabelled: In the recent years, the increasing applications of brain-computer interface (BCI) in rehabilitation programs have enhanced the chances of functional recovery for patients with neurological disorders. We presented and validated a BCI system with a lower-limb robot for short-term training of patients with spinal cord injury (SCI). The cores of this system included: (1) electroencephalogram (EEG) features related to motor intention reported through experiments and used to drive the robot; (2) a decision tree to determine the training mode provided for patients with different degrees of injuries.

Transcriptome Analysis Reveals the Role of GA in Regulating the Asynchronism of Floral Bud Differentiation and Development in Heterodichogamous (Batal.) Iljinskaja.

is an important medical plant owing to the diverse bioactive compounds in its leaves. However, the heterodichogamy with female and male functions segregation within protandry (PA) or protogyny (PG) may greatly affect seed quality and its plantations for medicinal use. To speculate on the factor playing the dominant role in regulating heterodichogamy in , based on phenotypic observations, our study performed a multi comparison transcriptome analysis on female and male buds (PG and PA types) using RNA-seq.

Responses of Physiology, Photosynthesis, and Related Genes to Saline Stress in subsp. (W. P. Fang) Q. Y. Xiang.

subsp. (W. P.

Effects of Anti-Vascular Endothelial Growth Factor Drugs Before and After Pars Plana Vitrectomy in Patients with Polypoidal Choroidal Vasculopathy and Vitreous Hemorrhage.

To compare the clinical effects of postoperative versus perioperative injection of anti-vascular endothelial growth factor (VEGF) drugs before and after pars plana vitrectomy (PPV) in patients with vitreous hemorrhage secondary to polypoidal choroidal vasculopathy (PCV). This was a retrospective study of patients who underwent PPV due to vitreous hemorrhage between October 2013 and June 2019 at Ningbo Eye Hospital. The patients who underwent PPV surgery due to PCV-secondary vitreous hemorrhage were included.

Genome-Wide Identification MIKC-Type MADS-Box Gene Family and Their Roles during Development of Floral Buds in Wheel Wingnut ().

MADS-box transcription factors (TFs) have fundamental roles in regulating floral organ formation and flowering time in flowering plants. In order to understand the function of MIKC-type MADS-box family genes in (Batal.) Iljinskaja, we first implemented a genome-wide analysis of MIKC-type MADS-box genes in .

Comparative analysis of the complete chloroplast genome between tetraploidy and diploidy of (Batal.) Iljinskaja.

(Batal.) Iljinskaja, a monotypic species in of Juglandaceae, is regarded as one of important medical plants in China. In order to reveal the alterations in chloroplast (cp) genome with nuclear genome duplication, we presented the complete cp genomes of , and firstly analyzed on the basis of ploidy type (tetraploid and diploid ).

Succession of the Resident Soil Microbial Community in Response to Periodic Inoculations.

To maintain the beneficial effects of microbial inoculants on plants and soil, repeated inoculation represents a promising option. Until now, the impacts of one-off inoculation on the native microbiome have been explored, but it remains unclear how long and to what extent the periodic inoculations would affect the succession of the resident microbiome in bulk soil. Here, we examined the dynamic responses of plant growth, soil functions, and the resident bacterial community in the bulk soil to periodic inoculations of phosphate-solubilizing and N-fixing bacteria alone or in combination.

[Synergistic effects of organic fertilizer coupled with phosphate-solubilizing and nitrogen-fixing bacteria on nutrient characteristics of yellow-brown soil under carbon deficiency].

Understanding the dynamics of phosphate-solubilizing and N-fixing bacteria on soil nutrient and related enzyme activity under different organic fertilizer proportions (OFP) could provide references for screening appropriate inoculant type, OFP, and fertilization period. Here, we set four OFP levels (mass ratio: 0%, 4%, 8%, 12%) and inoculated two phosphate-solubilizing bacteria (, ) and two N-fixing bacteria (, ) in the subtropical yellow-brown barren soil. After a 60-day soil incubation under controlled conditions (28 ℃, darkness), we examined the impacts of single/mixed applications of beneficial bacteria on soil available nutrients and related enzyme activities at different OFP levels and different sampling times (3rd, 8th, 16th, 30th, 45th, 60th day).

Localization and dynamic change of saponins in Cyclocarya paliurus (Batal.) Iljinskaja.

Cyclocarya paliurus is a unique tree species of that grows in southern China. The tree contains distinctive saponins in the leaf that has hypoglycemic and hypolipidemic effects. It was aimed to detect localization of saponins and suitable time of harvest for medicinal uses.

Integrated Effects of Co-Inoculation with Phosphate-Solubilizing Bacteria and N-Fixing Bacteria on Microbial Population and Soil Amendment Under C Deficiency.

The inoculation of beneficial microorganisms to improve plant growth and soil properties is a promising strategy in the soil amendment. However, the effects of co-inoculation with phosphate-solubilizing bacteria (PSB) and N-fixing bacteria (NFB) on the soil properties of typical C-deficient soil remain unclear. Based on a controlled experiment and a pot experiment, we examined the effects of PSB (M: and F: ), NFB (C: and B: ), and combined PSB and NFB treatments on C, N, P availability, and enzyme activities in sterilized soil, as well as the growth of seedlings grow in unsterilized soil.

A Scalable Approach for Dendrite-Free Alkali Metal Anodes via Room-Temperature Facile Surface Fluorination.

Alkali metals are attractive anode materials for advanced high-energy-density battery systems because of their high theoretical specific capacities as well as low electrochemical potential. However, severe dendrite growth as well as high chemical reactivity restrict their practical application in energy storage technologies. Herein, we propose a facile scalable solution-based approach to stabilize Li and Na anodes via the facile process of immersing the Li/Na metal in a nonhazardous ionic liquid 1-butyl-2,3-dimethylimidazolium tetrafluoroborate for several minutes at room temperature before battery assembly.

Geographic Variation in the Chemical Composition and Antioxidant Properties of Phenolic Compounds from (Batal) Iljinskaja Leaves.

has been widely used as an ingredient in functional foods in China. However, the antioxidant properties of phenolic compounds and the effect of the plant origin remain unclear. The present study evaluated the geographical variation of this plant in term of its phenolic composition and antioxidant activities based on leaf materials collected from five regions.

Antidiabetic Effect of Leaves Depends on the Contents of Antihyperglycemic Flavonoids and Antihyperlipidemic Triterpenoids.

has been used commonly to treat diabetes in China. However, the effective components and the effect of plant origin remain unclear. In this study, leaves with different chemical compositions were selected from five geographical locations, and their effects on streptozotocin (STZ)-induced diabetic mice were evaluated with both ethanol and aqueous extracts.