Publications by authors named "Xiangwen Qu"
Article Synopsis
- The study focuses on assessing the effectiveness and side effects of combining camrelizumab, an anti-PD-1 antibody, with chemotherapy for patients with early or locally advanced triple-negative breast cancer.
- The phase 3 trial involved 441 patients from various hospitals in China, where they were randomly assigned to receive either camrelizumab or a placebo along with standard chemotherapy over several weeks.
- Results showed a higher rate of pathological complete response—meaning no invasive tumors were detected—in the camrelizumab group (56.8%) compared to the placebo group (44.7%), indicating camrelizumab may enhance the effectiveness of chemotherapy.
A multifunctional surface-enhanced Raman scattering (SERS) platform integrating sensitive detection and drug resistance analysis was developed for Gram-positive bacteria. The substrate was based on self-assembled TiCT@Au NPs films and capture molecule phytic acid (IP6) to achieve specific capture of Gram-positive bacteria and different bacteria were analyzed by fingerprint signal. It had advantages of good stability and homogeneity (RSD = 8.
View Article and Find Full Text PDFNbC MXene self-assembled Au nanoparticles simultaneously based on electromagnetic enhancement and charge transfer for surface enhanced Raman scattering.
Spectrochim Acta A Mol Biomol Spectrosc
October 2023
Article Synopsis
- Two-dimensional transition metal carbonitrides, known as MXene, have shown promise in surface-enhanced Raman scattering (SERS) but face challenges due to relatively low enhancement levels.
- Researchers developed NbC-Au nanoparticle composites using an electrostatic method that enhance SERS performance through increased electromagnetic hot spots and improved surface properties.
- The technology demonstrates excellent detection limits for various dye molecules and biomolecules, along with consistent performance, making it a potential game-changer for fast, sensitive, and non-destructive detection applications.
Background: MicroRNAs (miRNAs) have been reported to play crucial role in the airway inflammatory diseases. However, the involvement of miR-206 in airway inflammatory diseases is still uninvestigated. The study aimed to explore the effect of miR-206 on lipopolysaccharide (LPS)-induced inflammation injury in MRC-5 cells, and point out a potential relevance for chronic obstructive pulmonary disease (COPD).
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