Publications by authors named "Xiangtao Zhang"
To examine the relationship between age at diagnosis of type 2 diabetes (T2DM) with cardiovascular and all-cause mortality in the U.S. population.
View Article and Find Full Text PDFBackground: The association between nonalcoholic fatty liver disease and cardiovascular disease is firmly established, yet the association between noninvasive liver fibrosis scores and cardiovascular events remains a topic of uncertainty. Our study aimed to explore the association between liver fibrosis and heart failure.
Methods And Results: The data set was from the National Health and Nutrition Examination Survey 2011 to 2018.
Article Synopsis
- This study examines the relationship between abnormal cardiac conditions and epilepsy using a Mendelian randomization approach, highlighting ongoing debates about how these conditions are linked.
- Researchers utilized genetic data from large databases to assess how conditions like atrial fibrillation (AF) and valvular heart disease (VHD) might influence the risk of developing epilepsy and vice versa.
- The results suggest a bidirectional association: AF and VHD can increase epilepsy risk, while having epilepsy may heighten the risk of developing these heart conditions, emphasizing the need for better screening processes in clinical practice.
The potential function of miR-135b-mediated JAK2/STAT3 signaling pathway during osteoblast differentiation.
Kaohsiung J Med Sci
September 2020
Article Synopsis
- MC3T3-E1 cells were divided into different groups to study the effects of miR-135b and JAK2/STAT3 signaling on osteoblast differentiation and cell viability.
- Various assays (MTT, ALP activity, alizarin red staining) were used to assess cell health and mineralization.
- Downregulating miR-135b enhanced JAK2 activity, improving cell viability and osteoblast differentiation, while miR-135b mimics reduced these functions, highlighting a regulatory role of miR-135b in osteogenesis through the JAK2/STAT3 pathway.
A multiple-anchored fluorescent probe ((((hexane-1,6-diylbis(2,7-bis(4-formyl)-phenyl)-9H-fluorine-9,9-diyl))-bis(hexane-6,1-diyl))-bis(9H-carbazole-9,3,6-triyl))-tetrakis(benzene-4,1-diyl))-tetraformyl-(8FP-2F) with eight aldehyde groups was designed and synthesized. The molecule has four branches and highly twisted structure. Furthermore, it tends to self-assemble into nanospheres, which is beneficial for gaseous analyte penetration and high fluorescence quantum efficiency.
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