Publications by authors named "Xiangtai Yu"
Article Synopsis
- The study focuses on a pathogenic fungus that poses significant risks to immunocompromised individuals, aiming to understand how it causes disease by examining fungal gene expression during infection.* -
- Researchers found that the expression of two specific MAPK proteins, Fus3 and Kss1, greatly increases during infection, and deleting both genes simultaneously reduces fungal presence in the host's organs and gut.* -
- The findings suggest that this MAPK signaling pathway is essential for the fungus's ability to persist and exhibit virulence, highlighting its importance in the organism's pathogenic capabilities.*
A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1.
Cell Host Microbe
September 2024
Candida albicans stably colonizes humans but is the leading cause of hospital-acquired fungemia. Traditionally, masking immunogenic moieties has been viewed as a tactic for immune evasion. Here, we demonstrate that C.
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