[The latest research progress of tinnitus related treatment].

Tinnitus is a kind of phantom hearing. The quality of life of millions of people around the world is affected by it. There is no data to prove that drugs can be cured.

Suppression of lncRNA MALAT1 Reduces LPS- or IL-17A-Induced Inflammatory Response in Human Middle Ear Epithelial Cells via the NF-B Signaling Pathway.

Otitis media (OM) is a common inflammatory disease of the middle ear cavity and mainly occurs in children. As a critical regulator of inflammation response, the nuclear factor kappa B (NF-B) pathway has been found to play an essential role in the pathogenesis of various human diseases. The aim of this study was to explore the potential mechanism under the inflammatory response of human middle ear epithelial cells (HMEECs).

[Study of the level of adiponectin in obstructive sleep apnea-hypopnea syndrome patients].

Objective: To investigate the change of fasting serum adiponectin in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients.

Method: Forty males with OSAHS and forty age-matched male normal controls were included in the study. Subjects in OSAHS group were divided into two sub-groups according to body mass index (BMI): obese OSAHS group (BMI > or =25, n=26) and non-obese group OSAHS (BMI <25, n=14).

[Clinical observation of 173 cases of partial laryngectomy].

Objective: To summarize and study the clinical effect of partial laryngectomy on laryngeal neoplasms.

Method: 173 cases of partial laryngectomy were performed. 6 kinds of operations were performed, 49 vertical laryngectomy, 39 supraglottic laryngectomy, 4 frontolateral laryngectomy, 47 extended partial laryngectomy ( with reservation of epiglottis and posterior part of thyroid cartilage), 17 pearson's surgery, 17 near-total laryngectomy with cricoglossal anastomosis.

[Expression of transforming growth factor-beta 1 matrix metalloproteinase-1 and its inhibitor in human middle ear cholesteatoma].

Objective: To investigate the expression of matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase-1 (TIMP-1) and transforming growth factor-beta 1 (TGF-beta 1) in human middle ear cholesteatoma.

Methods: Immunohistochemical staining was used to detect the expression of TGF-beta 1, MMP-1 and TIMP-1 in the cholesteatoma (41 cases) and the skin of external auditory meatus (15 cases).

Results: The percent of positive expression of TGF-beta 1, MMP-1 and TIMP-1 in cholesteatoma was 95.