A Polysiloxane Delivery Vehicle of Cyclic -Halamine for Biocidal Coating of Cellulose in Supercritical CO.

Cyclic -halamines are highly antimicrobial, very stable, and not susceptible to bacterial resistance. A polysiloxane delivery vehicle was synthesized to deliver cyclic imide -halamine onto cellulose via a benign and universal procedure that does not require a harmful solvent or chemical bonding. In brief, Knoevenagel condensation between barbituric acid and 4-hydroxybenzaldehyde furnished 5-(4-hydroxybenzylidene)pyrimidine-2,4,6-trione, whose phenolic O-H was subsequently reacted with the Si-H of poly(methylhydrosiloxane) (PMHS) via silane alcoholysis.