Publications by authors named "Xiangmin Yan"
Beef flavor plays a crucial role in consumer preference, yet research on this trait has been limited by past technological constraints. Intramuscular fat (IMF) is a key determinant of beef quality, influencing taste, marbling, and overall flavor. Xinjiang brown cattle (XBC), an indigenous breed from northern Xinjiang, China, presents significant variation in meat quality, with IMF content ranging from 0.
View Article and Find Full Text PDFIt is important to study the bacteria that cause endometritis to identify effective therapeutic drugs for dairy cows. In this study, 20% oxytetracycline was used to treat Holstein cows (n = 6) with severe endometritis. Additional 10 Holstein cows (5 for healthy cows, 5 for cows with mild endometritis) were also selected.
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- Xinjiang Brown cattle are an important dual-purpose breed in China, but there's limited genetic information available, prompting a study to analyze their genetic structure and diversity.
- Researchers used whole-genome sequencing and included other breeds to understand the background of Xinjiang Brown cattle, discovering that the grazing type (XBG) formed a stable population through crossbreeding.
- The study identified genetic differences between the grazing and housing types of Xinjiang Brown cattle, revealing significant genetic diversity and highlighting candidate genes associated with disease resistance and the endocrine system.
(1) Background: DNA double strand breaks (DSBs) are the most serious form of DNA damage that affects oocyte maturation and the physiological state of follicles and ovaries. Non-coding RNAs (ncRNAs) play a crucial role in DNA damage and repair. This study aims to analyze and establish the network of ncRNAs when DSB occurs and provide new ideas for next research on the mechanism of cumulus DSB.
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- The study focused on the proteomic analysis of longissimus dorsi muscle tissue from Kazakh and Xinjiang brown cattle to understand muscle production and development differences between the two breeds.
- Using advanced techniques, researchers identified 13,078 peptides and 1,874 proteins, revealing that Xinjiang brown cattle had 75 proteins upregulated and 44 downregulated compared to Kazakh cattle.
- Findings indicate that these differentially expressed proteins are involved in processes like adrenergic signaling, fatty acid degradation, and glutathione metabolism, highlighting their potential roles in cattle genetics and breeding.
Objective: With the rapid development of proteomics sequencing and RNA sequencing technology, multi-omics analysis has become a current research hotspot. Our previous study indicated that Xinjiang brown cattle have better meat quality than Kazakh cattle. In this study, Xinjiang brown cattle and Kazakh cattle were used as the research objects.
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- Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in muscle development, and this study aimed to investigate the differences in lncRNAs between Kazakh cattle and Xinjiang brown cattle.
- Using RNA-seq technology, the researchers identified 182 differentially expressed lncRNA transcripts, with 102 being upregulated and 80 downregulated in the longissimus dorsi muscle between the two cattle breeds.
- The study also revealed that these differentially expressed lncRNAs were linked to important signaling pathways, such as the mitogen-activated protein kinase and PI3k/Akt pathways, providing valuable insights into muscle biology in cattle.
Xinjiang brown cattle have better meat quality than Kazakh cattle. Circular RNAs (circRNAs) are a type of RNA that can participate in the regulation of gene transcription. Whether circRNAs are differentially expressed in the longissimus dorsi between these two types of cattle and whether differentially expressed circRNAs regulate muscle formation and differentiation are still unknown.
View Article and Find Full Text PDFIn this study, we examined the role of mRNAs and miRNAs in variations in intramuscular fat content in the longissimus dorsi muscle in Xinjiang brown cattle. Two groups of Xinjiang brown cattle with extremely different intramuscular fat content in the longissimus dorsi were selected for combined of miRNA and mRNA analysis using an RNA-Seq. In total, 296 mRNAs and 362 miRNAs were significantly differentially expressed, including 155 newly predicted miRNAs, 275 significantly upregulated genes, 252 significantly upregulated miRNAs, 21 significantly downregulated genes and 110 significantly downregulated miRNAs.
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