Publications by authors named "Xiangling Shao"

Correction for 'Development of a carbon quantum dots-based fluorescent Cu probe suitable for living cell imaging' by Qiang Qu , , 2012, , 5473-5475, https://doi.org/10.1039/C2CC31000G.

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Direct determination of cerebral metal ions in small volume biological samples is still the bottleneck for evaluating the roles that metal ions play in the physiological and pathological processes. In this work, selected copper ion (Cu(2+)) as a model, a facile and direct electrochemical method for detection of Cu(2+) has been developed on the basis of two new designed strategies: one is specific recognition molecule for Cu(2+)-AE-TPEA (N-(2-aminoethyl)-N,N',N'-tris(pyridine-2-yl-methyl)ethane-1,2-diamine); another is carbon dots (C-Dots) with high electrocatalytic activity. Based on the high affinity between TPEA and Cu(2+), the electrode assembled with C-Dot-TPEA hybridized nanocomposites shows high selectivity toward Cu(2+) over other metal ions, amino acids, and biological coexisting species, such as uric acid (UA), ascorbic acid (AA), and so on, which makes it possible to be used for determination of Cu(2+) in the complex brain system.

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An efficient strategy for selective fluorescent detection of Cu(2+) was developed based on the carbon quantum dots (CQDs) nanoconjugated with a specific organic molecule, amino TPEA, and further applied to intracellular sensing and imaging of Cu(2+) as a consequence of the fluorescence properties and the established low cytotoxicity of CQDs.

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A sensitive biosensor: A strategy for the intracellular imaging of Cu(2+) ions has been developed by integrating a recognition molecule, N-(2-aminoethyl)-N,N,N'tris(pyridin-2-ylmethyl)ethane-1,2-diamine (AE-TPEA), into a hybrid system composed of carbon and CdSe/ZnS quantum dots.

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