Identification and Validation of a Novel PANoptosis-related Gene Signatured for Osteosarcoma as Prognostic Model.

Objective: To construct and validate a prognostic model for osteosarcoma prognostication and therapeutic potential of PANoptosis- related genes.

Study Design: Observational study. Place and Duration of the Study: Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China, from August 2021 to January 2024.

Exploring expression levels of the cGAS-STING pathway genes in peripheral blood mononuclear cells of spinal tuberculosis patients.

Background: This study aimed to investigate the differential expression levels of the cGAS-STING pathway in peripheral blood mononuclear cells (PBMCs) of spinal tuberculosis (TB) patients with different progression and its feasibility as a diagnostic marker.

Methods: Peripheral blood and medical records of 25 patients with spinal TB and 10 healthy individuals, were prospectively collected and analyzed. PBMCs and serum were extracted from peripheral blood and the expression levels of the cGAS-STING pathway in PBMCs were measured by real-time PCR (RT-PCR) and serum interferon β (IFN-β) expression levels were measured by enzyme-linked immunosorbent assay (ELISA).

Anterior debridement combined with autogenous iliac bone graft fusion for the treatment of lower cervical tuberculosis: a multicenter retrospective study.

Background: This study aimed to analyze the clinical efficacy of one-stage anterior debridement of lower cervical tuberculosis using iliac crest bone graft fusion and internal fixation.

Materials And Methods: A retrospective analysis was performed on 48 patients with lower cervical tuberculosis admitted to multiple medical centers from June 2018 to June 2021. Among them, 36 patients had lesions involving two vertebrae and 12 patients had lesions involving more than three vertebrae.

Observation of Topological Edge States on α-BiBr Nanowires Grown on TiSe Substrates.

A time-reversal invariant two-dimensional (2D) topological insulator (TI) is characterized by the gapless helical edge states propagating along the perimeter of the system. However, the small band gap in the 2D TIs discovered so far hinders their applications. Recently, we predicted that single-layer BiBr is a 2D TI with a remarkable band gap and that α-BiBr crystals can host topological edge states at the step edges.

Epitaxial growth of Bi(110) and BiSethin films on a ferromagnetic insulator substrate of CrGeTe.

When a topological insulator (TI) is brought to the proximity of a ferromagnetic insulator (FMI), the breaking of the time-reversal symmetry may give rise to quantum anomalous Hall effect (QAHE). The physical properties of such TI-FMI systems are greatly affected by the interfacial structures of the components. Here, we report the growth and structural properties of Bi(110) and BiSethin films on a FMI of CrGeTe(CGT) substrate by scanning tunneling microscopy.

Magnetic and electric properties of single crystal MnI.

Multiferroic materials endowed with both dielectric and magnetic orders, are ideal candidates for a wide range of applications. In this work, we reported two phase transitions of MnIat 3.45 K and 4 K by systemically measuring the magnetic-field and temperature-dependent magnetization of the MnIthin flakes.

Observation of Topological Edge States at the Step Edges on the Surface of Type-II Weyl Semimetal TaIrTe.

Topological materials harbor topologically protected boundary states. Recently, TaIrTe, a ternary transition-metal dichalcogenide, was identified as a type-II Weyl semimetal with the minimal nonzero number of Weyl points allowed for a time-reversal invariant Weyl semimetal. Monolayer TaIrTe was proposed to host topological edge states, which, however, lacks of experimental evidence.