Influence of nitrogen speciation on Cd-induced toxicity in .

Nitrogen (N) plays an important role in plant growth and developmental metabolic processes, research on nitrogen speciation regulating Cd accumulation in duckweed is still limited. In this study, the effects of three nitrogen sources (NHCl, Ca(NO) and NHNO) on the growth, Cd accumulation, and photosynthetic parameters of ( ) were analyzed. The results showed that Cd enrichment in was significantly reduced ( 0.

Coordinated activity of a central pathway drives associative opioid analgesic tolerance.

Opioid analgesic tolerance, a root cause of opioid overdose and misuse, can develop through an associative learning. Despite intensive research, the locus and central pathway subserving the associative opioid analgesic tolerance (AOAT) remains unclear. Using a combination of chemo/optogenetic manipulation with calcium imaging and slice physiology, here we identify neuronal ensembles in a hierarchically organized pathway essential for AOAT.

Acetaminophen degradation in aqueous solution by the UV-LED-EC/Cl process.

In this study, electrochemically generated free chlorine (EC/Cl2) was activated by UV irradiation with a light emitting diode (LED) lamp at 275 nm to degrade acetaminophen (AAP, 2 μM) in aqueous solution. The potential at a RuO2-IrO2/Ti plate anode was set at 1.5 V vs.

Large-scale screening and characterization of Cd accumulation and ultrastructural deformation in duckweed.

Cadmium (Cd) pollution in soil, rivers and lakes is a serious problem due to the current industrialization and urbanization in China. Duckweeds are recognized as promising species for Cd phytoremediation. However, intraspecific variations in Cd accumulation in duckweeds remain largely unknown.

The relationship between the degree of brain edema regression and changes in cognitive function in patients with recurrent glioma treated with bevacizumab and temozolomide.

Background: This retrospective study aims to assess the impacts on cognitive status and quality of life in recurrent high-grade glioma patients treated with temozolomide (TMZ), either alone or in combination with bevacizumab (BEV), and explore the relationship between the brain edema regression, BEV use, and cognitive status.

Methods: A total of 125 patients with recurrent high-grade glioma were enrolled in this study, of which 65 patients were treated with BEV (5-10 mg/kg IV every 2 weeks) plus TMZ (200 mg/m every 28 days, d1-5), and 60 patients were treated with TMZ (200 mg/m every 28 days, d1-5) alone. The treatment response was evaluated using the Response Assessment in Neuro-Oncology (RANO) criteria.

Distribution, source identification, and health risk assessment of heavy metals in the soil-rice system of a farmland protection area in Hubei Province, Central China.

Heavy metal contamination in farmland soil is of great concern due to the threat to food security arising from the bioaccumulation of heavy metals in crops planted in contaminated soil, such as rice, corn, and vegetables. Cd is the main contaminant in both paddy soils and rice. The purpose of this study was to reveal the spatial distribution of 8 heavy metals (Cd, Cr, Ni, Cu, Pb, Zn, As, and Hg) in the farmland protection areas in northwestern Hubei Province and to evaluate their pollution status, sources, and health risks.

Chemical forms governing Cd tolerance and detoxification in duckweed (Landoltia punctata).

Duckweed (Landoltia punctata) is an ideal species to restore cadmium (Cd)-polluted waters due to its fast growth and easy harvesting. To understand its tolerance and detoxification mechanism, the Cd stress responses, subcellular Cd distribution and chemically bound Cd forms (especially protein-bound Cd) were surveyed in this study. L.

Effects of organic selenium on absorption and bioaccessibility of arsenic in radish under arsenic stress.

Arsenic (As) exposure poses a serious threat to human health. The present study investigated the effects of organic Se on As accumulation, migration, and As bioaccessibility in As-stressed radish. The results showed that organic Se can effectively block the accumulation of As in radish, reduce As bioaccessibility, and promote the conversion of As from inorganic to organic form.

Machine Learning Based on a Multiparametric and Multiregional Radiomics Signature Predicts Radiotherapeutic Response in Patients with Glioblastoma.

Methods: The MRI images, genetic data, and clinical data of 152 patients with GBM were analyzed. 122 patients from the TCIA dataset (training set: = 82; validation set: = 40) and 30 patients from local hospitals were used as an independent test dataset. Radiomics features were extracted from multiple regions of multiparameter MRI.

Effects of selenium on antioxidant enzyme activity and bioaccessibility of arsenic in arsenic-stressed radish.

Consuming arsenic (As)-contaminated vegetables is the main route of As exposure in humans. The present study focused on the alterations in antioxidant enzymatic activities and As bioaccessibility in As-contaminated radish subjected to Se. Compared to the CK group, the total As content in raw radish was reduced by 27.

[Measurements of Bacterial Community and Biodiversity from Activated Sludge for a Wastewater Treatment Containing Starch].

This study analyzes the microbial community and diversity composition of activated sludge in anoxic/oxic (A/O) treatment systems at different operation stages using Illumina MiSeq high-throughput sequencing to investigate the microbial community structure and diversity in activated sludge for starch wastewater treatment. The experimental results showed that the microbial community structure of activated sludge for starch production wastewater treatment in A/O systems was quite stable under the same wastewater condition, and that the dominant bacteria of the activated sludge were Proteobacteria, Bacteroidetes, Chloroflexi, Firmicutes, and Actinobacteria. The most important dominant bacterial group was Proteobacteria (45.

Correlations between slow pyrolysis characteristics and organic carbon structure of aquatic plant biomass.

Thermal analysis techniques have been widely used to characterize natural organic matter; in particular, thermal oxidation has been used to examine soil and sediment organic matter. However, few studies have characterized natural organic matter (NOM) by using slow thermal degradation under a N atmosphere. C nuclear magnetic resonance (NMR) spectroscopy, UV-Vis spectroscopy, and three-dimensional excitation and emission matrix (EEM) fluorescence spectroscopy were used to characterize aquatic plant biomass for the detailed interpretation of the structures of organic carbon during slow pyrolysis.

Assessing bioaccessibility of Se and I in dual biofortified radish seedlings using simulated in vitro digestion.

Selenium (Se) and iodine (I) are essential elements for humans, and biofortification of vegetables with these elements is an effective way to amend their deficiencies in the diet. In this study, the distribution and transformation of Se and I species were investigated in radish seedlings that were simultaneously supplemented with these two elements; the fate and the bioaccessibility of Se and I species were dynamically surveyed in the oral, gastric and intestinal phases using a simulated in vitro digestion method. The radish seedlings were cultivated in hydroponic conditions with Se (IV), Se (VI), I and IO (each 1 mg L).

F-Fluoromisonidazole positron emission tomography/CT-guided volumetric-modulated arc therapy-based dose escalation for hypoxic subvolume in nasopharyngeal carcinomas: A feasibility study.

Background: The purpose of this study is to investigate the feasibility of a simultaneously integrated boost to the hypoxic subvolume of nasopharyngeal carcinomas (NCPs) under the guidance of F-fluoromisonidazole (FMISO) positron emission tomography (PET)/CT using volumetric-modulated arc therapy (VMAT) and intensity-modulated radiotherapy (IMRT) techniques.

Methods: Eight patients with NPC were treated with simultaneous integrated boost-IMRT (treatment plan named IMRT70) with dose prescriptions of 70 Gy, 66 Gy, 60 Gy, and 54 Gy to the gross tumor volume (GTV), positive neck nodes, the planning target volume (PTV), and the clinically negative neck, respectively. Based on the same datasets, experimental plans with the same dose prescription plus a dose boost of 14 Gy (an escalation of 20% of the prescription dose) to the hypoxic volume target contoured on the pretreatment F-FMISO PET/CT imaging were generated using IMRT and VMAT techniques, respectively (represented by IMRT84 and VMAT84).

[Efficacy of MVP chemotherapy combined with concurrent radiotherapy for advanced non-small cell lung cancer].

Background: To observe the effects of MVP chemotherapy combined with concurrent radiotherapy for stage IIIB-IV non-small cell lung cancer.

Methods: Sixty-two patients with stage IIIB-IV non-small cell lung cancer were randomized into two groups, concurrent radiochemotherapy group and MVP che-motherapy group. All patients in two groups were treated with MVP regimen (mitomycin C 6 mg/m² on day 1, vindesine 2 mg/m² on days 1, 8, and cisplatin 80-100 mg/m²).

Changing knowledge, behavior, and practice related to universal precautions among hospital nurses in China.

Purpose: To evaluate the effect of an educational training program for hospital nurses on universal precautions in Changsha, Hunan Province, People's Republic of China.

Method: Using a quasi-experimental design, 50 of 100 randomly selected hospital nurses were randomly assigned to receive an educational intervention. Questionnaires were administered to the 100 nurses prior to and 4 months after the training.