Publications by authors named "Xiangjun Ying"
Article Synopsis
- Pelvic fractures can lead to urinary bladder injuries, typically showing symptoms like blood in urine, painful urination, and lower abdominal pain.* -
- This case report discusses a unique instance involving a 53-year-old man whose delayed pubic fracture penetrated the bladder and resulted in a secondary bladder stone.* -
- After surgery to remove the stone and fix the bladder, the patient improved significantly and remained symptom-free during follow-up until January 2023, highlighting the importance of monitoring for delayed injuries in such cases.*
Cordycepin inhibits kidney injury by regulating GSK-3β-mediated Nrf2 activation.
J Biochem Mol Toxicol
January 2024
We explored the role and mechanism of cordycepin (COR) in inhibiting kidney injury. A mouse model of kidney injury was established using cisplatin (CDDP), and the kidney function, histopathology, and ferroptosis indices in mice were detected after intervening with COR. The targets of COR-ferroptosis-kidney injury were analyzed by network pharmacology, based on which the association between glycogen synthase kinase-3 beta (GSK-3β) and COR was determined.
View Article and Find Full Text PDFLong noncoding RNA-LINC00478 promotes the progression of clear cell renal cell carcinoma through PBX3.
J Biochem Mol Toxicol
December 2022
Long noncoding RNAs play an important regulatory role in the development and progression of tumors. Our study found that LINC00478 was upregulated in clear cell renal cell carcinoma (ccRCC), so we made an in-depth exploration into its mechanism. In Caki-2 cells, we established the oe-LINC00478 cell line overexpressing LINC00478, and established underexpressing sh-LINC00478 cell line by short hairpin RNA silencing.
View Article and Find Full Text PDFGemcitabine (GEM) is one of the first choice drugs for treating bladder cancer. In this study, we loaded M1 macrophage-derived exosomes (M1-Exo) with GEM by ultrasonication technique to derive an M1-Exo-GEM drug delivery system, and then explored its effects on bladder cancer. After inducing M1 polarization of macrophages , ultracentrifugation was performed to obtain M1-Exo, followed by construction of M1-Exo-GEM via ultrasonication technique.
View Article and Find Full Text PDFBackground: Population-based analysis for the short-term non-bladder cancer related mortality among patients with non-metastatic bladder cancer is currently lacking. The objective of the current study was to assess and quantify cause of death after bladder cancer diagnosis.
Methods: The custom Surveillance, Epidemiology, and End Results (SEER) dataset for standardized mortality ratios (SMRs) was utilized to identify 24,074 patients who were diagnosed with nonmetastatic (M0) bladder cancer from 2014 to 2015.