Laser-induced CdS/TiO/graphene dual photoanodes for ratiometric self-powered photoelectrochemical sensor: an innovative approach for aflatoxin B1 detection.

A ratiometric self-powered photoelectrochemical sensor based on laser direct writing technology was constructed to address the problem that the conventional single-signal detection mode was susceptible to the influence of instrumentation and environmental factors, which interfered with the detection results. Laser-induced CdS/TiO/Graphene was prepared as dual photoanodes (PA1 and PA2), which were controlled by multiplexed switches to form a photocatalytic fuel cell with Pt cathode. By modifying the aptamer of aflatoxin B1 (AFB1) on the photoanode surface, the target was specifically captured to the electrode surface to form a biological complex, which increased the steric hindrance and affected the electron transfer, thus reducing the output signal of the sensor.

MXene-TiO-based photocatalytic fuel cell with bioresponsive controlled glucose release system: An innovative mode for Ochratoxin A detection.

Self-powered photocatalytic fuel cell (PFC)-based sensors incorporating bioelement recognition with fuel concentration-dependent output power have been developed for electrochemical analysis, but most involve poor energy conversion efficiency and are unsuitable for routine use. Herein, a self-powered and self-checking PFC bioanalysis platform under visible light for ultrasensitive screening of Ochratoxin A (OTA) was designed. Specifically, the self-powered photocatalytic fuel cell-based sensor was comprised of a photoanode fabricated with MXenes (TiC)-TiO and a cathode modified with Prussian blue (PB).

TiC MXene-anchored photoelectrochemical detection of exosomes by fabrication of CdS nanoparticles with enzyme-assisted hybridization chain reaction.

Exosomes that carry large amounts of tumor-specific molecular information have been identified as a potential non-invasive biomarker for early warning of cancer. In this work, we reported an enzyme-assisted photoelectrochemical (PEC) biosensor for quantification of exosomes based on the synthesis of TiC MXene/CdS composites with magnetic separation technology and hybridization chain reaction (HCR). First, exosomes were specifically bound between aptamer-labeled magnetic beads (CD63-MBs) and a cholesterol-labeled DNA anchor.