Intercultural competence of Chinese students abroad: An investigation under Sino-foreign Cooperative Education Programs.

The rapid growth of Sino-Foreign Cooperative Education Programs highlights the critical role of intercultural competence (IC) for Chinese students studying abroad. While extensive research exists on domestic contexts, empirical studies on Chinese students' experiences at foreign partner institutions remain scarce. This study addresses this gap by examining the intercultural competence of Chinese students in these programs and identifying key factors influencing their development.

Revolutionizing faculty's intrinsic work motivation in China: A novel serial mediation model integrating value-based leadership, growth mindset, and teaching self-efficacy.

This study presents a revolutionary understanding of how value-based leadership enhances the intrinsic work motivation of Chinese university faculty. A novel serial mediation model is introduced, highlighting the interplay between growth mindset and teaching self-efficacy in transmitting the impact of leadership to increased intrinsic motivation. Utilizing a comprehensive sample of 394 faculty members from across China, advanced SmartPLS 3.

[Regulatory effect of lactate on peripheral blood CD4 T cell subsets in patients with rheumatoid arthritis].

Objective: To investigate the serum lactate level in patients with rheumatoid arthritis (RA) and its relationship with disease activity, and to analyze the effect of sodium lactate on the activation of CD4 T cells, the ability of secreting cytokines and CD4T cell subsets in peripheral blood of the RA patients.

Methods: The peripheral blood of healthy controls (HC) and RA patients was collected, and the content of lactate in the supernatant was detected by lactate detection kit, the correlation between the content of lactate and the disease score of the RA patients was analyzed; the activation level of CD4 T cells, the proportion of CD4 T cell subsets and the cytokines secreted by CD4 T cells in peripheral blood of all the RA patients were detected by flow cytometry after being stimulated with sodium lactate.

Results: The serum lactate level in the RA patients (=66) was significantly higher than that in the HC (=60, < 0.

Triggering Chinese lecturers' intrinsic work motivation by value-based leadership and growth mindset: Generation difference by using multigroup analysis.

This cross-sectional study investigated the effects of value-based leadership and growth mindset on the intrinsic work motivation of Chinese lecturers. In addition, this study used age as a categorical moderator to investigate generational differences between the effects of Millennials and their predecessors. A sample of 518 lecturers from various Chinese universities was used to collect data, and SEM-PLS was used to analyse the data.

Transforming higher education institutions through EDI leadership: A bibliometric exploration.

This comprehensive bibliometric study analyzes 1820 journal articles from the Web of Science database to explore Equity, Diversity, and Inclusion (EDI) leadership in higher education institutions (HEIs). Utilizing co-citation and co-word analysis, the study identifies distinct thematic clusters. The co-citation analysis reveals five key themes: Race, Diversity, and Inclusion (RDI), Diversity, Leadership, and Self-Efficacy (DLSE), Gender Dynamics and Leadership Challenges, Women's Representation in Academic Medicine Leadership, and Transformational Leadership in HEIs.

IL-27 enhances peripheral B cell glycolysis of rheumatoid arthritis patients via activating mTOR signaling.

Our previous study found that increased serum IL-27 could promote rheumatoid arthritis (RA) B cell dysfunction via activating mTOR signaling pathway. This study aimed to explore the effects of IL-27 on B cell metabolism and clarify the mechanisms via which IL-27 enhancing glycolysis to induce B cells hyperactivation. Peripheral CD19 B cells were purified from healthy controls (HC) and RA patients and then cultured with or without anti-CD40/CpG and glycolysis inhibitor 2-deoxy-D-glucose (2-DG) or mTOR inhibitor rapamycin.

Targeting protein arginine methyltransferase 5 in cancers: Roles, inhibitors and mechanisms.

The protein arginine methyltransferase 5 (PRMT5) as the major type II arginine methyltransferase catalyzes the mono- and symmetric dimethylation of arginine residues in both histone and non-histone proteins. Recently, increasing evidence has demonstrated that PRMT5 plays an indispensable role in the occurrence and development of various human cancers by promoting the cell proliferation, invasion, and migration. It has become a promising and valuable target in the cancer epigenetic therapy.