Publications by authors named "Xiangge Ma"

The brain undergoes atrophy and cognitive decline with advancing age. The utilization of brain age prediction represents a pioneering methodology in the examination of brain aging. This study aims to develop a deep learning model with high predictive accuracy and interpretability for brain age prediction tasks.

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This study investigates the relationship between modifiable risk factors and dementia subtypes using data from 460,799 participants in the UK Biobank. Utilizing univariate Cox proportional hazards regression models, we examined the associations between 83 modifiable risk factors and the risks of all-cause dementia (ACD), Alzheimer's disease (AD), and vascular dementia (VD). Composite scores for different domains were generated by aggregating risk factors associated with ACD, AD, and VD, respectively, and their joint associations were assessed in multivariable Cox models.

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In the ever-evolving landscape of deep learning (DL), the transformer model emerges as a formidable neural network architecture, gaining significant traction in neuroimaging-based classification and regression tasks. This paper presents an extensive examination of transformer's application in neuroimaging, surveying recent literature to elucidate its current status and research advancement. Commencing with an exposition on the fundamental principles and structures of the transformer model and its variants, this review navigates through the methodologies and experimental findings pertaining to their utilization in neuroimage classification and regression tasks.

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Article Synopsis
  • The concept of 'brain age' uses neuroimaging data as a biomarker to understand cognitive health and neurodegenerative conditions, with machine learning (ML) and deep learning (DL) advancing its estimation over the past decade.
  • A comprehensive review analyzes 52 studies from 2020 to 2024, evaluating different ML and DL models and their effectiveness in predicting brain age across various age groups.
  • The review highlights achievements and challenges in the field, providing insights to guide future research and improve strategies for early intervention in neurodegenerative diseases.
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