Experimental validation of zero-group-velocity feature guided waves in a welded joint utilizing the pitch-catch measurement technique with air-coupled ultrasonic transducers.

Zero-Group-Velocity (ZGV) Lamb waves in elastic plates had been conducted extensive theoretical and experimental researches in the field of ultrasonic nondestructive testing. The ZGV modes in complex structures had been studied theoretically, but less attention had been paid to their experimental investigation. This paper reports the experimental observation of Zero-Group-Velocity Feature Guided Waves (ZGV-FGWs) in a welded joint using the pitch-catch measurement technique with air-coupled ultrasonic transducers.

Log odds of positive lymph nodes (LODDS)-based novel nomogram for survival estimation in patients with invasive micropapillary carcinoma of the breast.

Background: Invasive micropapillary carcinoma (IMPC) of the breast is known for its high propensity for lymph node (LN) invasion. Inadequate LN dissection may compromise the precision of prognostic assessments. This study introduces a log odds of positive lymph nodes (LODDS) method to address this issue and develops a novel LODDS-based nomogram to provide accurate prognostic information.

Radiomics-clinical nomogram for preoperative lymph node metastasis prediction in esophageal carcinoma.

Objectives: This research aimed to develop a radiomics-clinical nomogram based on enhanced thin-section CT radiomics and clinical features for the purpose of predicting the presence or absence of metastasis in lymph nodes among patients with resectable esophageal squamous cell carcinoma (ESCC).

Methods: This study examined the data of 256 patients with ESCC, including 140 cases with lymph node metastasis. Clinical information was gathered for each case, and radiomics features were derived from thin-section contrast-enhanced CT with the help of a 3D slicer.

Nomogram-Based Risk Stratification to Identify Patients with T3N0M0 Breast Cancer with Survival Benefit from Postmastectomy Radiotherapy.

Background: The survival benefit of postmastectomy radiotherapy (PMRT) for patients with T3N0M0 breast cancer remains controversial. This study aimed to identify patients with a survival benefit from PMRT by developing a novel risk stratification model.

Patients And Methods: The study recruited 2062 patients with pT3N0M0 breast cancer from the Surveillance, Epidemiology, and End Results (SEER) database who underwent mastectomy between 2010 and 2019.

Investigating the prognostic role of lncRNAs associated with disulfidptosis-related genes in clear cell renal cell carcinoma.

Introduction: Renal cell carcinoma (RCC) is a grave malignancy that poses a significant global health burden with over 400,000 new cases annually. Disulfidptosis, a newly discovered programmed cell death process, is linked to the actin cytoskeleton, which plays a vital role in maintaining cell shape and survival. The role of disulfidptosis is poorly depicted in the clear cell histologic variant of RCC (ccRCC).

Validation of zero-group-velocity feature guided waves in a welded joint.

Extensive research has been conducted on zero-group-velocity (ZGV) Lamb waves in elastic plates, demonstrating significant progress in the field of nondestructive testing. However, there is a scarcity of studies focusing on ZGV modes in complex structures. In this paper, we present our research investigating the presence of ZGV feature guided waves (FGWs) in a welded joint.

Exploring oncogenes for renal clear cell carcinoma based on G protein-coupled receptor-associated genes.

G protein-coupled receptors (GPCRs) are a class of receptors on cell membranes that regulate various biological processes in cells, such as cell proliferation, differentiation, migration, apoptosis, and metabolism, by interacting with G proteins. However, the role of G protein-coupled receptors in predicting the prognosis of renal clear cell carcinoma is still unknown. The transcriptome data and clinical profiles of renal clear cell carcinoma patients, were downloaded from TCGA databases, and the validation group data were downloaded from number GSE167573, including 63 tumor samples and 14 normal samples.

Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis.

Clear-cell renal cell carcinoma (ccRCC) appears as the most common type of kidney cancer, the carcinogenesis of which has not been fully elucidated. Tumor heterogeneity plays a crucial role in cancer progression, which could be largely deciphered by the implement of scRNA-seq. The bulk and single-cell RNA expression profile is obtained from TCGA and study conducted by Young et al.

Coordinating single-cell and bulk RNA-seq in deciphering the intratumoral immune landscape and prognostic stratification of prostate cancer patients.

Introduction: Prostate cancer is a common cancer among male population. The aberrant expression of histone modifiers has been identified as a potential driving force in numerous cancer types. However, the mechanism of histone modifiers in the development of prostate cancer remains unknown.

Risk-dependent conditional survival analysis and annual hazard rate of inflammatory breast cancer.

Purpose: The real-time prognosis of patients with inflammatory breast cancer (IBC) after surviving for several years was unclear. We aimed to estimate survival over time in IBC using conditional survival (CS) and annual hazard functions.

Patients And Methods: This study recruited 679 patients diagnosed with IBC between 2010 and 2019 from the Surveillance, Epidemiology, and End Results (SEER) database.

A novel conditional survival nomogram for monitoring real-time prognosis of non-metastatic triple-negative breast cancer.

Background: Conditional survival (CS) is defined as the possibility of further survival after patients have survived for several years since diagnosis. This may be highly valuable for real-time prognostic monitoring, especially when considering individualized factors. Such prediction tools were lacking for non-metastatic triple-negative breast cancer (TNBC).

Effects of Probiotic Supplementation on Nutrient Intake, Ghrelin, and Adiponectin Concentrations in Diabetic Hemodialysis Patients.

Objective: The paper aimed to explore the effect of probiotic supplementation on nutrient intake, Ghrelin, and adiponectin concentrations in diabetic hemodialysis patients.

Methods: A total of 86 patients with diabetic nephropathy who received hemodialysis treatment in the Department of Nephrology of the First People's Hospital of Shanghai from May 2019 to March 2021 were selected as the research subjects, including 52 male patients and 34 female patients, with an average age of 56.57 ± 4.

Association of Androgen-Receptor Gene Mutations with the Copy Number of Androgen-Receptor Silk Protein A Complex and Glutathione-S-Transferases T1 and M1 in Prostate Cancer Patients.

Objective: The purpose of our work was to explore the association of mutations in the androgen receptor gene and copy numbers of the androgen-receptor silk protein A complex with glutathione-S-transferases T1 and M1 in prostate cancer patients.

Materials And Methods: Eighty-five patients with PC and 85 healthy controls were included in the study. Fasting peripheral venous blood was collected, whole blood genomic DNA was extracted, and AR gene-receptor genotype was detected by a high-resolution melting curve analysis detection technology.

Conditional survival analysis and real-time prognosis prediction for cervical cancer patients below the age of 65 years.

Background: Survival prediction for cervical cancer is usually based on its stage at diagnosis or a multivariate nomogram. However, few studies cared whether long-term survival improved after they survived for several years. Meanwhile, traditional survival analysis could not calculate this dynamic outcome.

Development of a nomogram for predicting grade 2 or higher acute hematologic toxicity of cervical cancer after the pelvic bone marrow sparing radiotherapy.

Background: Acute hematologic toxicity (HT) is a common complication during radiotherapy of cervical cancer which may lead to treatment delay or interruption. Despite the use of intensity-modulated radiation therapy (IMRT) with the pelvic bone marrow (PBM) sparing, some patients still suffer from acute HT. We aimed to identify predictors associated with HT and develop a nomogram for predicting grade 2 or higher (G2+) acute HT in cervical cancer following the PBM sparing strategy.

Development and Validation a Survival Prediction Model and a Risk Stratification for Elderly Locally Advanced Breast Cancer.

Purpose: we aimed to develop an individualized survival prediction model for elderly locally advanced breast cancer (LABC) and stratify its risk to assist in the treatment and follow-up of patients.

Methods: Elderly LABC data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The best model was screened using Cox, least absolute shrinkage and selection operator (LASSO) and best subset regression to construct the nomogram.

Effects of etoposide combined with cisplatin on prognosis of patients with castration-resistant prostate cancer who failed castration treatment.

Objective: To determine the influences of etoposide combined with cisplatin on prognosis of patients with castration-resistant prostate cancer (CRPC) who failed castration treatment.

Methods: A total of 100 patients with metastatic CRPC who failed castration treatment in our hospital from January 2015 to January 2017 were retrospectively analyzed. The patients were divided into a control group (n=59) treated with docetaxel combined with prednisone and an experimental group (n=41) treated with etoposide combined with cisplatin (EP).

Long non-coding RNA MAGI2 inactivates STAT3 pathway to inhibit prostate cancer cell proliferation via acting as a microRNA-424-5p sponge.

Aberrant expression of long non-coding RNAs (lncRNAs) that results in sustained activation of cell growth promoting pathways is an important mechanism in driving prostate cancer progression. In the present study, we explored differentially expressed lncRNAs in two microarray datasets of prostate benign and malignant tissues. We found that was one of the most downregulated lncRNAs in prostate tumors, which was further confirmed in our collected clinical samples.

Nomogram Predicting the Risk of Locoregional Recurrence After Mastectomy for Invasive Micropapillary Carcinoma of the Breast.

Background: The risk of locoregional recurrence (LRR) after mastectomy for breast invasive micropapillary carcinoma (IMPC) remains poorly defined. We aimed to construct an effective prognostic nomogram to estimate the individualized risk of LRR for providing accurate information for long-term follow-up.

Patients And Methods: A total of 388 patients with breast IMPC were included in the current study.

Analysis on coupled vibration of piezoelectric ceramic stack with two piezoelectric ceramic elements.

A longitudinally polarized piezoelectric ceramic stack with two piezoelectric ceramic elements is an important part of sandwich piezoelectric transducers. The three-dimensional coupled vibration of piezoelectric ceramic stack is analyzed. Since the longitudinal and radial dimensions of particular piezoelectric ceramic stacks are approximately equal, one-dimensional theory cannot be used for analysis.

Analysis of a Cascaded Piezoelectric Ultrasonic Transducer with Three Sets of Piezoelectric Ceramic Stacks.

To increase the ultrasonic intensity and power of a piezoelectric transducer, a cascaded piezoelectric ultrasonic transducer with the three sets of piezoelectric ceramic stacks is analyzed. The cascaded piezoelectric ultrasonic transducer consists of four metal cylinders and three sets of piezoelectric ceramic stacks in the longitudinal direction. In analysis, the electromechanical equivalent circuit of the cascaded piezoelectric ultrasonic transducer is obtained, as well as the resonance/anti-resonance frequencies equations.