Publications by authors named "Xiang-hong Ji"
[Effects of transient receptor potential V6 silence on proliferation and apoptosis of trophoblasts].
Zhonghua Fu Chan Ke Za Zhi
October 2012
Article Synopsis
- The study aimed to explore how silencing the TRPV6 gene affects the growth and programmed cell death (apoptosis) of HTR-8/SVneo trophoblast cells.
- Researchers used siRNA to target TRPV6 and found that its silencing resulted in decreased TRPV6 mRNA expression over time, leading to significant inhibition of cell proliferation and increased rates of apoptosis.
- Results showed that after TRPV6 silencing, proliferation rates dropped significantly at various time points, while apoptosis rates increased notably compared to control groups, indicating that TRPV6 plays a crucial role in trophoblast cell regulation.
Objective: To investigate the relationship of S100B protein expression and the pathogenesis of early-onset and late-onset preeclampsia.
Methods: Sixty patients with preeclampsia who received caesarean section at Qingdao Municipal Hospital from October 2010 to September 2011 were enrolled in this study. Thirty cases were early-onset preeclampsia (referred as early-onset preeclampsia group, < 34 weeks), and the other 30 cases were late-onset preeclampsia (referred as late-onset preeclampsia group, ≥ 34 weeks).
[Efficacy and delivery outcomes of women underwent double-catheter epidural block during labor].
Zhonghua Fu Chan Ke Za Zhi
November 2010
Objective: To investigate the efficacy and pregnancy outcomes of women receiving double-catheter epidural block in labor analgesia, and compare the results with single-catheter epidural block.
Methods: A double-blind clinical trial was conducted on 206 full-term singleton primiparas, aged 25 - 35 and at the 37 - 42 weeks of gestation who delivered at the Department of Obstetrics, Qingdao Municipal Hospital from August 2006 to December 2008, which were randomly divided into two groups: double-catheter epidural block (group D, n = 103) and single-catheter epidural-block (group S, n = 103). Women in group D were given mixture of 0.
[Study on the relation between concentration of circulating non-host fetal DNA in pregnant women and pre-eclampsia].
Zhonghua Fu Chan Ke Za Zhi
December 2005
Objective: To explore the diagnostic value of plasma fetal DNA level in preeclampsia.
Methods: Thirty cases of pregnant women with preeclampsia (at 33 weeks and 3 days) and 30 cases of normal pregnant women (at 34 weeks and 3 days) were selected. All the pregnant women carried a male fetus by B-ultrasound, and were sampled at gestational 20 weeks, third trimester and at 1 hour, 3 hours, 6 hours after delivery.
[Study on the time selection of pregnancy and delivery in women with systemic lupus erythematosus].
Zhonghua Fu Chan Ke Za Zhi
August 2004
Objective: To analyze the appropriate time selection of pregnancy and delivery in women with systemic lupus erythematosus (SLE).
Methods: Twenty-nine pregnancies in women with SLE in our hospital from 1998 to 2003 were retrospectively analyzed regarding the selection of appropriate time of pregnancy and delivery.
Results: All patients did not take any cytotoxic medicine for at least 6 months before pregnancy.