Effect of Suo Quan Wan on the bladder function of aging rats based on the β-adrenoceptor.

Suo Quan Wan (SQW) has been used to treat lower urinary tract symptoms (LUTS) in elderly patients for hundreds of years in China. β-adrenoceptors (β-ARs), particularly β-adrenoceptor (β-AR), was reported to be important in the bladder dysfunction of the elderly. The present study was conducted to explore the effect of β-AR, and particularly the β-adrenoceptor, in aging rat bladder function and to test the therapeutic effect of SQW on LUTS in an aging rat model based on the β-adrenoceptor.

[One new truxillic amide compound from Abrus mollis leaves].

The butanol extract part was extracted and isolated with water, alcohol and different organic solvents from Abrus mollis leaves. 6 compounds were isolated and purified using various column chromatographies and identified with the spectral techniques such as UV, MS, TLC, HPLC and NMR. The structures of 6 compounds were trigonelline (1), praline (2), alanine anhydride (3), (Z)-N-(4-hydroxycinnamoyl)tyrosine (4), (E)-N-(4-hydroxycinnamoyl)tyrosine (5), and abrusamide C (6).

[Primary Pharmacodynamic Study on Chuanping Dropping Pills].

Objective: To study the antitussive, antiasthmatic, and expectorant effects of Chuanoing dropping pills.

Methods: Histamine-acetylcholine induced asthma, ovalbumin sensitization, pulmonary overflow, spiral strip trachea of guinea pig, lung strip of guinea pig, ammonia water or citric acid induced cough of mice, and phenol red expectoration of mice were carried out.

Results: Chuanping dripping pills significantly prolonged the incubation induced by histamine-acetylcholine, reduced the reaction stage of ovalbumin sensitization of guinea pig with asthma, inhibited the increase of pulmonary overflow on histamine induced asthma, reduced the contraction of smooth muscle and lung strip by histamine induced asthma on guinea pig, reduced cough times on ammonia or citrate acid caused mice, and increased the output on mice tracheal phenol red.

[Analysis of volatile oil in pre and post processed pieces of Eriobotrya japonica by GC-MS].

Objective: To analyze the chemical components of the volatile oil in processed pieces of Eriobotrya japonica by GC-MS.

Methods: The volatile oil was obtained by steam distillation. The amount of the components from the volatile oil were determinated by area normalization method.